Journal
EXPERT REVIEW OF MEDICAL DEVICES
Volume 6, Issue 6, Pages 641-651Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1586/ERD.09.46
Keywords
automated; infectious disease; molecular diagnostics; PCR; point of care
Categories
Funding
- MRC/EPSRC through the Technology Strategy Board
- NIHR i4i
- European Community's Seventh Framework Program [FP7/2007-2013]
- PortFastFlu and the Countess Dowager Eleanor Peel Trust
- Engineering and Physical Sciences Research Council [TS/G001898/1] Funding Source: researchfish
- EPSRC [TS/G001898/1] Funding Source: UKRI
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The last 2 years has seen an exponential rise in the amount of research funding made available for the development of rapid diagnostic devices for infectious agents of medical importance. This review reports on several such projects. These highlight the development of fully automated devices for rapid diagnostics, ranging from fully automated real-time PCR-based detection methods to fully automated PCR- and array-based machines for the detection and typing of influenza. This review will also highlight the importance of refocusing work on classical immunoassay techniques, showing how biosensor-based immunoassays can greatly enhance existing assays and at a much reduced cost to molecular-based methods.
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