Journal
EXPERT REVIEW OF CLINICAL IMMUNOLOGY
Volume 5, Issue 6, Pages 693-702Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1586/ECI.09.53
Keywords
asthma; autoimmune disease; immune system regulation; T-regulatory cell; vitamin D; vitamin D deficiency
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The effects of vitamin D on bone metabolism and calcium homeostasis have long been recognized. Emerging evidence has implicated vitamin D as a critical regulator of immunity, playing a role in both the innate and cell-mediated immune systems. Vitamin D deficiency has been found to be associated with several immune-mediated diseases, susceptibility to infection and cancer. Recently, there has been increasing interest in the possible link between vitamin D and asthma. Further elucidation of the role of vitamin D in lung development and immune system function may hold profound implications for the prevention and treatment of asthma.
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