Targeting TRPC6 channels in oesophageal carcinoma growth

Importance of the field: Oesophageal carcinoma ranks among the ten most frequent cancers worldwide. The special growing site and malignant nature make it difficult to be completely treated by surgical operation and radiotherapy or chemotherapy. Discovery of new therapeutic targets responsible for the rapid proliferation of oesophageal carcinoma cells could help to treat this disease. Areas covered in this review: Over the past two decades, studies have revealed a critical role of Ca