Related references
Note: Only part of the references are listed.Antivirulence drugs to target bacterial secretion systems
Christian Baron
CURRENT OPINION IN MICROBIOLOGY (2010)
Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents
Bo Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Targeting Type III Secretion in Yersinia pestis
Ning J. Pan et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Phase 1/2 Double-Blind, Placebo-Controlled, Dose Escalation, Safety, and Pharmacokinetic Study of Pagibaximab (BSYX-A110), an Antistaphylococcal Monoclonal Antibody for the Prevention of Staphylococcal Bloodstream Infections, in Very-Low-Birth-Weight Neonates
Leonard E. Weisman et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Computer-Aided Identification of Recognized Drugs as Pseudomonas aeruginosa Quorum-Sensing Inhibitors
Liang Yang et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Towards Gram-negative antivirulence drugs: New inhibitors of HldE kinase
Nicolas Desroy et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Tethered thiazolidinone dimers as inhibitors of the bacterial type III secretion system
Toni Kline et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Microbial quorum sensing: a tool or a target for antimicrobial therapy?
Sheetal Raina et al.
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY (2009)
Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules
Paul Williams et al.
CURRENT OPINION IN MICROBIOLOGY (2009)
Quorum sensing inhibitors: a patent overview
Jiachuan Pan et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2009)
Has the era of untreatable infections arrived?
David M. Livermore
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2009)
N-Hydroxybenzimidazole Inhibitors of the Transcription Factor LcrF in Yersinia: Novel Antivirulence Agents
Oak K. Kim et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Quorum sensing and social networking in the microbial world
Steve Atkinson et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2009)
A Quorum-Sensing Antagonist Targets Both Membrane-Bound and Cytoplasmic Receptors and Controls Bacterial Pathogenicity
Lee R. Swem et al.
MOLECULAR CELL (2009)
Inhibitors and Antagonists of Bacterial Quorum Sensing
Nanting Ni et al.
MEDICINAL RESEARCH REVIEWS (2009)
The two-component system QseEF and the membrane protein QseG link adrenergic and stress sensing to bacterial pathogenesis
Nicola C. Reading et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Aryl Acid Adenylating Enzymes Involved in Siderophore Biosynthesis: Fluorescence Polarization Assay, Ligand Specificity, and Discovery of Non-nucleoside Inhibitors via High-Throughput Screening
Joao Neres et al.
BIOCHEMISTRY (2008)
Synthesis of and evaluation of lipid A modification by 4-substituted 4-deoxy arabinose analogs as potential inhibitors of bacterial polymyxin resistance
T. Kline et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Identification of novel inhibitors of bacterial surface enzyme Staphylococcus aureus Sortase A
Bala Chandra Chenna et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Pyrogallol and its analogs can antagonize bacterial quorum sensing in Vibrio harveyi
Nanting Ni et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Selective killing of nonreplicating mycobacteria
Ruslana Bryk et al.
CELL HOST & MICROBE (2008)
An Inhibitor of Gram-Negative Bacterial Virulence Protein Secretion
Heather B. Felise et al.
CELL HOST & MICROBE (2008)
Discovery of virulence factors of pathogenic bacteria
Hsing-Ju Wu et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2008)
Antivirulence as a new antibacterial approach for chemotherapy
Sonia Escaich
CURRENT OPINION IN CHEMICAL BIOLOGY (2008)
Control of gene expression by type III secretory activity
Evan D. Brutinel et al.
CURRENT OPINION IN MICROBIOLOGY (2008)
What is in the pipeline for Gram-negative pathogens?
George H. Talbot
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2008)
Staphylococcus aureus - Probing for host weakness?
Rana L. B. C. Camargo et al.
JOURNAL OF BACTERIOLOGY (2008)
Inhibition of siderophore biosynthesis in Mycobacterium tuberculosis with nucleoside bisubstrate analogues:: Structure-activity relationships of the nucleobase domain of 5′-O-[N-(salicyl)sulfamoyl]adenosine
Joao Neres et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Cyclic peptide inhibitors of staphylococcal virulence prepared by Fmoc-based thiolactone peptide synthesis
Elizabeth A. George et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
The biology and future prospects of antivirulence therapies
Lynette Cegelski et al.
NATURE REVIEWS MICROBIOLOGY (2008)
Teichoic acids and related cell-wall glycopolymers in Gram-positive physiology and host interactions
Christopher Weidenmaier et al.
NATURE REVIEWS MICROBIOLOGY (2008)
Sortase as a Target of Anti-Infective Therapy
A. W. Maresso et al.
PHARMACOLOGICAL REVIEWS (2008)
A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence
Chia-I Liu et al.
SCIENCE (2008)
Targeting QseC signaling and virulence for antibiotic development
David A. Rasko et al.
SCIENCE (2008)
Inhibition of quorum sensing-controlled virulence factor production in Pseudomonas aeruginosa by south Florida plant extracts
Allison Adonizio et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)
Design, synthesis, and Multivariate quantitative structure-activity relationship of Salicylanilides-Potent inhibitors of type III secretion in Yersinia
Markus K. Dahlgren et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Inhibitors of type III secretion in Yersinia:: Design, synthesis and multivariate QSAR of 2-arvisulfonylamino-benzanilides
Anna M. Kauppi et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Generation of virulence factor variants in Staphylococcus aureus Biofilms
Jeremy A. Yarwood et al.
JOURNAL OF BACTERIOLOGY (2007)
Novel anti-infection agents: Small-molecule inhibitors of bacterial transcription factors
Todd E. Bowser et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Infection control by antibody disruption of bacterial quorum sensing signaling
Junguk Park et al.
CHEMISTRY & BIOLOGY (2007)
Aaptamines as sortase A inhibitors from the tropical sponge Aaptos aaptos
Kyoung Hwa Jang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Inhibitors of pathogen intercellular signals as selective anti-infective compounds
Biliana Lesic et al.
PLOS PATHOGENS (2007)
Activation of inhibitors by sortase triggers irreversible modification of the active site
Anthony W. Maresso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Salicylidene acylhydrazides that affect type III protein secretion in Salmonella enterica serovar Typhimurium
Aurel Negrea et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
Inhibition of type III secretion in Salmonella enterica serovar typhimurium by small-molecule inhibitors
Debra L. Hudson et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model
Louise D. Christensen et al.
MICROBIOLOGY-SGM (2007)
Treatment of Staphylococcus aureus biofilm infection by the quorum-sensing inhibitor RIP
Naomi Balaban et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
A Staphylococcus aureus regulatory system that responds to host heme and modulates virulence
Victor J. Torres et al.
CELL HOST & MICROBE (2007)
Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle
Leslie Bailey et al.
FEBS LETTERS (2007)
Virstatin inhibits dimerization of the transcriptional activator ToxT
Elizabeth A. Shakhnovich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Genomic approaches to understanding bacterial virulence
Laura S. Burrack et al.
CURRENT OPINION IN MICROBIOLOGY (2007)
Siderophore-based iron acquisition and pathogen control
Marcus Miethke et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2007)
Targeting virulence: a new paradigm for antimicrobial therapy
Anne E. Clatworthy et al.
NATURE CHEMICAL BIOLOGY (2007)
Drugs for bad bugs: confronting the challenges of antibacterial discovery
David J. Payne et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Protein delivery into eukaryotic cells by type III secretion machines
Jorge E. Galan et al.
NATURE (2006)
Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria
Jerome S. Pinkner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Design, synthesis and evaluation of peptidomimetics based on substituted bicyclic 2-pyridones -: Targeting virulence of uropathogenic E-coli
Veronica Aberg et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Treatment of Chlamydia trachomatis with a small molecule inhibitor of the Yersinia type III secretion system disrupts progression of the chlamydial developmental cycle
K. Wolf et al.
MOLECULAR MICROBIOLOGY (2006)
A functional dlt operon, encoding proteins required for incorporation of D-alanine in teichoic acids in gram-positive bacteria, confers resistance to cationic antimicrobial peptides in Streptococcus pneumoniae
Marta Kovacs et al.
JOURNAL OF BACTERIOLOGY (2006)
Flavonols inhibit sortases and sortase-mediated Staphylococcus aureus clumping to fibrinogen
Sam Sik Kang et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2006)
Alanine esters of enterococcal lipoteichoic acid play a role in biofilm formation and resistance to antimicrobial peptides
Francesca Fabretti et al.
INFECTION AND IMMUNITY (2006)
Staphylococcus quorum sensing in biofilm formation and infection
KF Kong et al.
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2006)
An in vitro screen of bacterial lipopolysaccharide biosynthetic enzymes identifies an inhibitor of ADP-heptose biosynthesis
GP De Leon et al.
CHEMISTRY & BIOLOGY (2006)
Sortases and the art of anchoring proteins to the envelopes of gram-positive bacteria
LA Marraffini et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2006)
Cationic host defense (antimicrobial) peptides
KL Brown et al.
CURRENT OPINION IN IMMUNOLOGY (2006)
Multiple sensors control reciprocal expression of Pseudomonas aeruginosa regulatory RNA and virulence genes
I Ventre et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Inhibition of aryl acid adenylation domains involved in bacterial siderophore synthesis
M Miethke et al.
FEBS JOURNAL (2006)
Lipopolysaccharide (Endotoxin)-host defense antibacterial peptides interactions: Role in bacterial resistance and prevention of sepsis
Yosef Rosenfeld et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)
Resistance to antibiotics: Are we in the post-antibiotic era?
AJ Alanis
ARCHIVES OF MEDICAL RESEARCH (2005)
Reduced susceptibility of Staphylococcus aureus to vancomycin and platelet microbicidal protein correlates with defective autolysis and loss of accessory gene regulator (agr) function
G Sakoulas et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Functional genomics in antibacterial drug discovery
C Freiberg et al.
DRUG DISCOVERY TODAY (2005)
Inhibition of the D-alanine:D-alanyl carrier protein ligase from Bacillus subtilis increases the bacterium's susceptibility to antibiotics that target the cell wall
JJ May et al.
FEBS JOURNAL (2005)
Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis
JA Ferreras et al.
NATURE CHEMICAL BIOLOGY (2005)
Identity and effects of quorum-sensing inhibitors produced by Penicillium species
TB Rasmussen et al.
MICROBIOLOGY-SGM (2005)
Iron-source preference of Staphylococcus aureus infections
EP Skaar et al.
SCIENCE (2004)
Large-scale identification of genes required for full virulence of Staphylococcus aureus
BM Benton et al.
JOURNAL OF BACTERIOLOGY (2004)
Inhibition of the Staphylococcus aureus sortase transpeptidase SrtA by phosphinic peptidomimetics
RG Kruger et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2004)
Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice
H Wu et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2004)
A heptosyltransferase mutant of Pasteurella multocida produces a truncated lipopolysaccharide structure and is attenuated in virulence
M Harper et al.
INFECTION AND IMMUNITY (2004)
Discovery of diarylacrylonitriles as a novel series of small molecule sortase A inhibitors
KB Oh et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Antibacterial peptides: basic facts and emerging concepts
HG Boman
JOURNAL OF INTERNAL MEDICINE (2003)
A continuum of anionic charge: Structures and functions of D-Alanyl-Teichoic acids in gram-positive bacteria
FC Neuhaus et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2003)
Share Paper
