4.5 Review

The development of pyrrolobenzodiazepines as antitumour agents

Related references

Note: Only part of the references are listed.
Article Oncology

A phase I trial of SJG-136 (NSC#694501) in advanced solid tumors

Yelena Y. Janjigian et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY (2010)

Review Biochemistry & Molecular Biology

Antibody-drug conjugates: targeted drug delivery for cancer

Stephen C. Alley et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2010)

Article Chemistry, Medicinal

Structure-Activity Relationships of Monomeric C2-Aryl Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) Antitumor Agents

Dyeison Antonow et al.

JOURNAL OF MEDICINAL CHEMISTRY (2010)

Review Oncology

Pyrrolo[2,1-c][1,4]benzodiazepine as a Scaffold for the Design and Synthesis of Anti-Tumour Drugs

Laura Cipolla et al.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2009)

Review Cell Biology

DNA Interstrand Crosslink Repair in Mammalian Cells

Kevin M. Mccabe et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2009)

Article Biochemistry & Molecular Biology

Synthesis, DNA binding, and cytotoxicity studies of pyrrolo [2,1-c][1,4]benzodiazepine-anthraquinone conjugates

Ahmed Kamal et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2007)

Article Chemistry, Medicinal

DC-81-Indole conjugate agent induces mitochondria mediated apoptosis in human melanoma A375 cells

Wan-Ping Hu et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2007)

Article Biochemical Research Methods

LC-MS/MS assay and dog pharmacokinetics of the dimeric pyrrolobenzodiazepine SJG-136 (NSC 694501)

Sarah A. Buhrow et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2006)

Article Chemistry, Medicinal

Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole conjugates with remarkable DNA-binding affinity

A Kamal et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)

Article Chemistry, Medicinal

Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids as potential DNA-binding agents

A Kamal et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)

Article Biochemistry & Molecular Biology

The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks

LJ Niedernhofer et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Chemistry, Medicinal

Synthesis of novel C2 and C2-C8 linked pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide hybrids as DNA-binding agents

A Kamal et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2003)

Article Biotechnology & Applied Microbiology

Development of potent monoclonal antibody auristatin conjugates for cancer therapy

SO Doronina et al.

NATURE BIOTECHNOLOGY (2003)

Article Chemistry, Medicinal

Unsymmetrical DNA cross-linking agents: Combination of the CBI and PBD pharmacophores

M Tercel et al.

JOURNAL OF MEDICINAL CHEMISTRY (2003)

Article Chemistry, Multidisciplinary

Synthesis of novel C2-aryl pyrrolobenzodiazepines (PBDs) as potential antitumour agents

N Cooper et al.

CHEMICAL COMMUNICATIONS (2002)

Article Chemistry, Multidisciplinary

Design and synthesis of a novel DNA-DNA interstrand adenine-guanine cross-linking agent

Q Zhou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)