Journal
EXPERT OPINION ON EMERGING DRUGS
Volume 16, Issue 2, Pages 235-245Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1517/14728214.2011.552427
Keywords
hair cells; noise-induced hearing loss; permanent hearing loss; pharmacological protection; temporary hearing loss
Categories
Funding
- NIDCD NIH HHS [R01 DC003685, R01 DC003685-12] Funding Source: Medline
Ask authors/readers for more resources
Areas covered: The review describes the epidemiology, pathology and pathophysiology of NIHL in experimental animals and humans. The underlying molecular mechanisms of damage are then discussed as a basis for therapeutic approaches to ameliorate the loss of auditory function. Finally, studies in military, industrial and recreational settings are evaluated. Literature was searched using the terms ''noise-induced hearing loss'' and ''noise trauma''. Expert opinion: NIHL, in principle, can be prevented. With the current pace of development, oral drugs to protect against NIHL should be available within the next 5 -- 10 years. Positive results from ongoing trials combined with additional laboratory tests might accelerate the time from the bench to clinical treatment.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available