4.2 Review

Emerging drugs for respiratory syncytial virus infection

Journal

EXPERT OPINION ON EMERGING DRUGS
Volume 14, Issue 2, Pages 207-217

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1517/14728210902946399

Keywords

antisense RNA; anti-viral drugs; fusion inhibitors; RSV; therapeutic antibodies

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Although respiratory syncytial virus (RSV) was discovered > 40 years ago, treatment remains largely supportive. There are no safe and effective vaccines or specific treatments other than prophylaxis with passive antibody therapy (palivizumab). However, there are good reasons to think that the scene may soon change. As the pace of development of anti-viral drugs accelerates and optimism over vaccines increases, novel therapies are set to make a major impact in the management of this very common infection. The use and effect of such interventions are not easy to anticipate, but could ultimately include the interruption of RSV's transmission resulting in profound changes to the impact ozf RSV on human health.

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