Related references
Note: Only part of the references are listed.Desbutyl-Lumefantrine Is a Metabolite of Lumefantrine with Potent In Vitro Antimalarial Activity That May Influence Artemether-Lumefantrine Treatment Outcome
Rina P. M. Wong et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2011)
Using rapid diagnostic tests as source of malaria parasite DNA for molecular analyses in the era of declining malaria prevalence
Deus S. Ishengoma et al.
MALARIA JOURNAL (2011)
Pharmacokinetics of Artemether-Lumefantrine and Artesunate-Amodiaquine in Children in Kampala, Uganda
Julia Mwesigwa et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
New Fixed-Dose Artesunate-Mefloquine Formulation against Multidrug-Resistant Plasmodium falciparum in Adults: a Comparative Phase IIb Safety and Pharmacokinetic Study with Standard-Dose Nonfixed Artesunate plus Mefloquine
S. Krudsood et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
The rise and fall of the antimalarial Lapdap: a lesson in pharmacogenetics
Lucio Luzzatto
LANCET (2010)
Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial
Antoinette K. Tshefu et al.
LANCET (2010)
Anti-malarial drugs and the prevention of malaria in the population of malaria endemic areas
Brian Greenwood
MALARIA JOURNAL (2010)
Rapid and effective malaria control in Cambodia through mass administration of artemisinin-piperaquine
Jianping Song et al.
MALARIA JOURNAL (2010)
Declining in efficacy of a three-day combination regimen of mefloquine-artesunate in a multi-drug resistance area along the Thai-Myanmar border
Kesara Na-Bangchang et al.
MALARIA JOURNAL (2010)
Pharmacokinetics of artemether and dihydroartemisinin in healthy Pakistani male volunteers treated with artemether-lumefantrine
Shabana Ali et al.
MALARIA JOURNAL (2010)
Artemisinin Directly Targets Malarial Mitochondria through Its Specific Mitochondrial Activation
Juan Wang et al.
PLOS ONE (2010)
Artemisinins and the biological basis for the PfATP6/SERCA hypothesis
Sanjeev Krishna et al.
TRENDS IN PARASITOLOGY (2010)
Pharmacokinetics and Bioequivalence Evaluation of Two Fixed-Dose Tablet Formulations of Dihydroartemisinin and Piperaquine in Vietnamese Subjects
Nguyen Trong Chinh et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Pharmacokinetics and Ex Vivo Pharmacodynamic Antimalarial Activity of Dihydroartemisinin-Piperaquine in Patients with Uncomplicated Falciparum Malaria in Vietnam
Dao Van Hoang Nguyen et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Structure, Function, Regulation and Polymorphism of Human Cytochrome P450 2A6
Yuan Ming Di et al.
CURRENT DRUG METABOLISM (2009)
Progress in the development of piperaquine combinations for the treatment of malaria
Umberto D'Alessandro
CURRENT OPINION IN INFECTIOUS DISEASES (2009)
Novel Metabolites of Amodiaquine Formed by CYP1A1 and CYP1B1: Structure Elucidation Using Electrochemistry, Mass Spectrometry, and NMR
Tove Johansson et al.
DRUG METABOLISM AND DISPOSITION (2009)
Blood-brain barrier transporters and response to CNS-active drugs
Bradley L. Urquhart et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2009)
Discovery, mechanisms of action and combination therapy of artemisinin
Liwang Cui et al.
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2009)
In Vivo Selection of Plasmodium falciparum Parasites Carrying the Chloroquine-Susceptible pfcrt K76 Allele after Treatment with Artemether-Lumefantrine in Africa
Christin Sisowath et al.
JOURNAL OF INFECTIOUS DISEASES (2009)
Cytochrome P450-mediated metabolism in the human gut wall
Kirstin Thelen et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2009)
Pharmacogenetics of antimalarial drugs: effect on metabolism and transport
Reinhold Kerb et al.
LANCET INFECTIOUS DISEASES (2009)
Understanding the pharmacokinetics of Coartem (R)
Abdoulaye Djimde et al.
MALARIA JOURNAL (2009)
Artemisinin Resistance in Plasmodium falciparum Malaria.
Arjen M. Dondorp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Changes in the Treatment Responses to Artesunate-Mefloquine on the Northwestern Border of Thailand during 13 Years of Continuous Deployment
Verena Ilona Carrara et al.
PLOS ONE (2009)
Pharmacogenomics of CYP3A: considerations for HIV treatment
Sukhwinder S. Lakhman et al.
PHARMACOGENOMICS (2009)
Mefloquine neurotoxicity: A literature review
Stephen Toovey
TRAVEL MEDICINE AND INFECTIOUS DISEASE (2009)
Chinese Propriety Medicines: An Alternative Modernity? The Case of the Anti-Malarial Substance Artemisinin in East Africa
Elisabeth Hsu
MEDICAL ANTHROPOLOGY (2009)
Clinical pharmacology of artemisinin-based combination therapies
Francesca T. Aweeka et al.
CLINICAL PHARMACOKINETICS (2008)
Functional Role of Ile264 in CYP2C8: Mutations Affect Haem Incorporation and Catalytic Activity
Rajinder Singh et al.
DRUG METABOLISM AND PHARMACOKINETICS (2008)
Relationship Between Drugs and Functional Activity of Various Mammalian P-Glycoproteins (ABCB1)
Suresh Ambudkar et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2008)
The role of anti-malarial drugs in eliminating malaria
Nicholas J. White
MALARIA JOURNAL (2008)
Evidence of Artemisinin-Resistant Malaria in Western Cambodia
Harald Noedl et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Pharmacogenetic tools for malaria and TB in the Developing World
Pedro Eduardo Ferreira et al.
PERSONALIZED MEDICINE (2008)
Adherence and efficacy of supervised versus non-supervised treatment with artemether/lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Bangladesh:: a randomised controlled trial
Md. Mushfiqur Rahman et al.
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE (2008)
Artemisinin and a series of novel endoperoxide Antimalarials exert early effects on digestive vacuole morphology
Maria del Pilar Crespo et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)
Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects
Magnus Ingelman-Sundberg et al.
PHARMACOLOGY & THERAPEUTICS (2007)
Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar
Achuyt Bhattarai et al.
PLOS MEDICINE (2007)
Specific pharmacokinetic interaction between lumefantrine and monodesbutyl-benflumetol in Plasmodium falciparum
Peter Starzengruber et al.
WIENER KLINISCHE WOCHENSCHRIFT (2007)
Pharmacokinetics of two paediatric artesunate-mefloquine drug formulations in the treatment of uncomplicated falciparum malaria in Gabon
Michael Ramharter et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2007)
Population pharmacokinetics of amodiaquine and desethylamodiaquine in pediatric patients with uncomplicated falciparum malaria
Sofia Friberg Hietala et al.
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2007)
Selection of pfmdr1 mutations after amodiaquine monotherapy and amodiaquine plus artemisinin combination therapy in East Africa
Gabrielle Holmgren et al.
INFECTION GENETICS AND EVOLUTION (2007)
Amodiaquine metabolism is impaired by common polymorphisms inCYP2C8: Implications for malaria treatment in Africa
S. Parikh et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2007)
CYP2C8 and antimalaria drug efficacy
J. P. Gill et al.
PHARMACOGENOMICS (2007)
ABCB1 pharmacogenetics:: Progress, pitfalls, and promise
L. W. Chinn et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2007)
Prevalence of UGT1A9 and UGT2B7 nonsynonymous single nucleotide polymorphisms in West African, Papua New Guinean, and North American populations
Rajeev K. Mehlotra et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2007)
Characterization of human urinary metabolites of the antimalarial piperaquine
J. Tarning et al.
DRUG METABOLISM AND DISPOSITION (2006)
The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicated falciparum malaria
Rose McGready et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2006)
Efficacy of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Cambodia
Mey Bouth Denis et al.
TROPICAL MEDICINE & INTERNATIONAL HEALTH (2006)
Role of P glycoprotein in absorption of novel antimalarial drugs
Andrew Crowe et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)
MDR1 gene polymorphisms are associated with neuropsychiatric adverse effects of mefloquine
Albert L. H. J. Aarnoudse et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2006)
Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum
Petra Rohrbach et al.
EMBO JOURNAL (2006)
Identification and characterization of CYP3A4*20, a novel rare CYP3A4 allele without functional activity
A Westlind-Johnsson et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2006)
Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multildrug resistance protein 1 (MRP1/Al3CC1)
IJ Létourneau et al.
PHARMACOGENETICS AND GENOMICS (2005)
Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4) that are present in human red cell membranes
CP Wu et al.
BIOCHEMICAL PHARMACOLOGY (2005)
Cytochrome P-450 1A1 gene polymorphisms and risk of breast cancer: A HuGE review
LF Masson et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2005)
In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem)
C Sisowath et al.
JOURNAL OF INFECTIOUS DISEASES (2005)
The disposition of oral amodiaquine in Papua New Guinean children with falciparum malaria
FW Hombhanje et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2005)
CYP2C8 polymorphism frequencies among malaria patients in Zanzibar
I Cavaco et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Piperaquine - A resurgent antimalarial drug
TME Davis et al.
DRUGS (2005)
Disposition of artesunate and dihydroartemisinin after administration of artesunate suppositories in children from Papua New Guinea with uncomplicated malaria
HA Karunajeewa et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number
RN Price et al.
LANCET (2004)
Pyronaridine, a novel modulator of P-glycoprotein-mediated multidrug resistance in tumor cells in vitro and in vivo
J Qi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Antimalarial drug toxicity - A review
WRJ Taylor et al.
DRUG SAFETY (2004)
Validated assays for human cytochrome P450 activities
RL Walsky et al.
DRUG METABOLISM AND DISPOSITION (2004)
Synergism between amodiaquine and its major metabolite, desethylamodiaquine, against Plasmodium falciparum in vitro
ST Mariga et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Comparative pharmacokinetics of intramuscular artesunate and artemether in patients with severe falciparum malaria
TT Hien et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs
L Villeneuve et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Identification of human cytochrome P450s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data
XQ Li et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2003)
Pharmacokinetics and electrocardiographic pharmacodynamics of artemether-lumefantrine (Riamet®) with concomitant administration of ketoconazole in healthy subjects
G Lefèvre et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2002)
Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases
KF Ilett et al.
DRUG METABOLISM AND DISPOSITION (2002)
Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8:: A new high affinity and turnover enzyme-specific probe substrate
XQ Li et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Differential effects of 4-aminoquinoline-containing antimalarial drugs on hemoglobin digestion in Plasmodium falciparum-infected erythrocytes
O Famin et al.
BIOCHEMICAL PHARMACOLOGY (2002)
Combination therapy for malaria - The way forward?
F Nosten et al.
DRUGS (2002)
Oral artesunate dose-response relationship in acute falciparum malaria
BJ Angus et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
Desbutyl-benflumetol, a novel antimalarial compound:: In vitro activity in fresh isolates of Plasmodium falciparum from Thailand
H Noedl et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2001)
Pharmacokinetic interactions of antimalarial agents
PT Giao et al.
CLINICAL PHARMACOKINETICS (2001)
Interactions of racemic mefloquine and its enantiomers with P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT
YT Pham et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2000)
Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand:: a prospective study
F Nosten et al.
LANCET (2000)
Evaluation of the genetic component of variability in CYP3A4 activity:: a repeated drug administration method
V Özdemir et al.
PHARMACOGENETICS (2000)
Role of cytochrome P450 3A in the metabolism of mefloquine in human and animal hepatocytes
F Fontaine et al.
LIFE SCIENCES (2000)
Pharmacokinetics and bioequivalence evaluation of three commercial tablet formulations of mefloquine when given in combination with dihydroartemisinin in patients with acute uncomplicated falciparum malaria
K Na-Bangchang et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2000)