Journal
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY
Volume 6, Issue 1, Pages 105-114Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1517/17425250903490418
Keywords
antiretroviral therapy; HIV; lamivudine; nucleoside reverse transcriptase inhibitor
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Lamivudine is a nucleoside reverse transcriptase inhibitor that is widely used for the treatment of HIV-1 infection in combination with other antiretrovirals. It is a highly effective agent that can be dosed once or twice daily due to its long intracellular half-life. it also has one of the best tolerability and long-term safety profiles among all antiretroviral agents and continues to be preferred as part of initial or subsequent combination therapy in HIV-infected patients.
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