Related references
Note: Only part of the references are listed.LC-MS/MS Mediated Absolute Quantification and Comparison of Bile Salt Export Pump and Breast Cancer Resistance Protein in Livers and Hepatocytes across Species
Na Li et al.
ANALYTICAL CHEMISTRY (2009)
Species-specific toxicity of diclofenac and troglitazone in primary human and rat hepatocytes
Birthe Lauer et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2009)
Absolute Difference of Hepatobiliary Transporter Multidrug Resistance-Associated Protein (MRP2/Mrp2) in Liver Tissues and Isolated Hepatocytes from Rat, Dog, Monkey, and Human
Na Li et al.
DRUG METABOLISM AND DISPOSITION (2009)
Physiologically Based Pharmacokinetic Modeling to Predict Transporter-Mediated Clearance and Distribution of Pravastatin in Humans
Takao Watanabe et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Absolute quantification of multidrug resistance-associated protein 2 (MRP2/ABCC2) using liquid chromatography tandem mass spectrometry
Na Li et al.
ANALYTICAL BIOCHEMISTRY (2008)
Effect of plasma protein binding on in vitro-in vivo correlation of biliary excretion of drugs evaluated by sandwich-cultured rat hepatocytes
Hajime Fukuda et al.
DRUG METABOLISM AND DISPOSITION (2008)
Identification of interspecies difference in efflux transporters of hepatocytes from dog, rat, monkey and human
Meng Li et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
Primary hepatocytes as a model to analyze species-specific toxicity and drug metabolism
Gregor Tuschl et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2008)
Involvement of Mrp2 (Abcc2) in biliary excretion of moxifloxacin and its metabolites in the isolated perfused rat liver
Salwa Ahmed et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2008)
Quantitative atlas of membrane transporter proteins:: Development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria
Junichi Kamiie et al.
PHARMACEUTICAL RESEARCH (2008)
Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2
Lauren M. Aleksunes et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2008)
Localization of P-gp (Abcb1) and Mrp2 (Abcc2) in freshly isolated rat hepatocytes
Daniel A. J. Bow et al.
DRUG METABOLISM AND DISPOSITION (2008)
Changes in gene expression induced by tienilic acid and sulfamethoxazole: Testing the danger hypothesis
Stephanie R. Pacitto et al.
JOURNAL OF IMMUNOTOXICOLOGY (2007)
Challenges and opportunities with modelling and simulation in drug discovery and drug development
T. Lave et al.
XENOBIOTICA (2007)
Involvement of breast cancer resistance protein (ABCG2) in the biliary excretion mechanism of fluoroquinolones
Tomohiro Ando et al.
DRUG METABOLISM AND DISPOSITION (2007)
Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines
Constanze Hilgendorf et al.
DRUG METABOLISM AND DISPOSITION (2007)
In vitro-in vivo correlation of hepatobiliary drug clearance in humans
G. Ghibellini et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2007)
Multidrug resistance-associated proteins 3, 4, and 5
Piet Borst et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
The bile salt export pump
Bruno Stieger et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: From in vitro to in vivo
O. V. Nemirovskiy et al.
ANALYTICAL BIOCHEMISTRY (2007)
Differences in the transport of the antiepileptic drugs phenytoin, levetiracetarn and carbamazepine by human and mouse P-glycoprotein
Steffen Baltes et al.
NEUROPHARMACOLOGY (2007)
Involvement of breast cancer resistance protein (BCRP/ABCG2) in the biliary excretion and intestinal efflux of troglitazone sulfate, the major metabolite of troglitazone with a cholestatic effect
Junichi Enokizono et al.
DRUG METABOLISM AND DISPOSITION (2007)
Translational regulation of rat multidrug resistance-associated protein 2 expression is mediated by upstream open reading frames in the 5 ' untranslated region
Yuanyuan Zhang et al.
MOLECULAR PHARMACOLOGY (2007)
Prediction of drug-induced intrahepatic cholestasis: in vitro screening and QSAR analysis of drugs inhibiting the human bile salt export pump
Aki Sakurai et al.
EXPERT OPINION ON DRUG SAFETY (2007)
Functional analysis of mouse and monkey multidrug resistance-associated protein 2 (Mrp2)
Mizuki Ninomiya et al.
DRUG METABOLISM AND DISPOSITION (2006)
Kinetic analyses for species differences in P-glycoprotein-mediated drug transport
Miki Katoh et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2006)
Differential involvement of Mrp2 (Abcc2) and Bcrp (Abcg2) in biliary excretion of 4-methylumbelliferyl glucuronide and sulfate in the rat
Maciej J. Zamek-Gliszczynski et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: A resource for investigations into drug disposition
K. Bleasby et al.
XENOBIOTICA (2006)
Breast cancer resistance protein (BCRP/ABCG2) is expressed by progenitor cells/reactive ductules and hepatocytes and its expression pattern is influenced by disease etiology and species type: Possible functional consequences
Sara Vander Borght et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2006)
High-speed screening and QSAR analysis of human ATP-binding cassette transporter ABCB11 (bile salt export pump) to predict drug-induced intrahepatic cholestasis
Hiroyuki Hirano et al.
MOLECULAR PHARMACEUTICS (2006)
Use of cryopreserved human hepatocytes in sandwich culture to measure hepatobiliary transport
Yi-an Bi et al.
DRUG METABOLISM AND DISPOSITION (2006)
Transport by vesicles of glycine- and taurine-conjugated bile salts and taurolithocholate 3-sulfate: A comparison of human BSEP with rat Bsep
H Hayashi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2005)
Population pharmacokinetic modeling for enterohepatic recirculation in Rhesus monkey
MG Shou et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2005)
Cyclosporine markedly raises the plasma concentrations of repaglinide
LI Kajosaari et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2005)
Differential regulation of the human MRP2 and MRP3 gene expression by glucocorticoids
L Pulaski et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2005)
Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin
M Hirano et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Variable expression of MRP2 (ABCC2) in human placenta: Influence of gestational age and cellular differentiation
HEMZ Schwabedissen et al.
DRUG METABOLISM AND DISPOSITION (2005)
Analysis of ABCC6 (MRP6) in normal human tissues
K Beck et al.
HISTOCHEMISTRY AND CELL BIOLOGY (2005)
Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver
G Merino et al.
MOLECULAR PHARMACOLOGY (2005)
Interspecies scaling of biliary excreted drugs: A comparison of everal methods
I Mahmood
JOURNAL OF PHARMACEUTICAL SCIENCES (2005)
Functional analysis of dog multidrug resistance-associated protein 2 (Mrp2) in comparison with rat Mrp2
M Ninomiya et al.
DRUG METABOLISM AND DISPOSITION (2005)
Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice
Y Tanaka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Quantification of C-reactive protein in the serum of patients with rheumatoid arthritis using multiple reaction monitoring mass spectrometry and 13C-labeled peptide standards
E Kuhn et al.
PROTEOMICS (2004)
Possible involvement of the drug transporters P glycoprotein and multidrug resistance-associated protein Mrp2 in disposition of azithromycin
M Sugie et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
The MRP-related and BCRP/ABCG2 multidrug resistance proteins: Biology, substrate specificity and regulation
A Haimeur et al.
CURRENT DRUG METABOLISM (2004)
Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis
A Figge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Absolute quantification of specific proteins in complex mixtures using visible isotope-coded affinity tags
Y Lu et al.
ANALYTICAL CHEMISTRY (2004)
Variation of peptide transporter (PepT1 expression in Caco-2 cells as a function and HPT1) of cell origin
I Behrens et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2004)
Exploring the quantitative relationship between the level of MDR1 transcript, protein and function using digoxin as a marker of MDR1-dependent drug efflux activity
J Taipalensuu et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2004)
LPS-induced downregulation of MRP2 and BSEP in human liver is due to a posttranscriptional process
MGL Elferink et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2004)
Absolute quantification of the model biomarker prostate-specific antigen in serum by LC-MS/MS using protein cleavage and isotope dilution mass spectrometry
DR Barnidge et al.
JOURNAL OF PROTEOME RESEARCH (2004)
Human hepatocytes as a tool for studying toxicity and drug metabolism
MJ Gómez-Lechón et al.
CURRENT DRUG METABOLISM (2003)
ABCG2 transports sulfated conjugates of steroids and xenobiotics
M Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS
SA Gerber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Absolute quantification of the G protein-coupled receptor rhodopsin by LC/MS/MS using proteolysis product peptides and synthetic peptide standards
DR Barnidge et al.
ANALYTICAL CHEMISTRY (2003)
Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats
VE Kostrubsky et al.
TOXICOLOGICAL SCIENCES (2003)
Endogenous drug transporters in in vitro and in vivo models for the prediction of drug disposition in man
LB Goh et al.
BIOCHEMICAL PHARMACOLOGY (2002)
The human bile salt export pump: Characterization of substrate specificity and identification of inhibitors
JA Byrne et al.
GASTROENTEROLOGY (2002)
Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs
DX Sun et al.
PHARMACEUTICAL RESEARCH (2002)
Targeted proteomics of low-level proteins in human plasma by LC/MSn:: Using human growth hormone as a model system
SL Wu et al.
JOURNAL OF PROTEOME RESEARCH (2002)
Interspecies scaling of biliary excreted drugs
I Mahmood et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2002)
Sirolimus/cyclosporine/tacrolimus interactions on bile flow and biliary excretion of immunosuppressants in a subchronic bile fistula rat model
M Deters et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
Enterohepatic circulation - Physiological, pharmacokinetic and clinical implications
MS Roberts et al.
CLINICAL PHARMACOKINETICS (2002)
Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile salt export pump (Bsep) by troglitazone and troglitazone sulfate
C Funk et al.
TOXICOLOGY (2001)
Role of transport proteins in drug absorption, distribution and excretion
A Ayrton et al.
XENOBIOTICA (2001)
Sinusoidal efflux of taurocholate is enhanced in Mrp2-deficient rat liver
H Akita et al.
PHARMACEUTICAL RESEARCH (2001)
Lessons from the glitazones: a story of drug development
EAM Gale
LANCET (2001)
Characterization of the mouse bile salt export pump overexpressed in the baculovirus system
J Noe et al.
HEPATOLOGY (2001)
Organic anion-transporting potypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver
GA Kullak-Ublick et al.
GASTROENTEROLOGY (2001)
Expression and regulation of hepatic drug and bile acid transporters
V Lecureur et al.
TOXICOLOGY (2000)
Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver
B Stieger et al.
GASTROENTEROLOGY (2000)
Hepatic transport of bile salts
GA Kullak-Ublick et al.
SEMINARS IN LIVER DISEASE (2000)
Hepatobiliary transport
GA Kullak-Ublick et al.
JOURNAL OF HEPATOLOGY (2000)
Share Paper
