Related references
Note: Only part of the references are listed.Fluorescence anisotropy: from single molecules to live cells
Claudiu C. Gradinaru et al.
ANALYST (2010)
Development of a high-throughput fluorescence polarization assay for the discovery of phosphopantetheinyl transferase inhibitors
Benjamin P. Duckworth et al.
ANALYTICAL BIOCHEMISTRY (2010)
A fluorescence polarization-based assay for the identification and evaluation of calmodulin antagonists
Tomonori Arai et al.
ANALYTICAL BIOCHEMISTRY (2010)
A Fluorescence Anisotropy Assay for the Muscarinic M1 G-protein-Coupled Receptor
Kristin G. Huwiler et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2010)
Development and Validation of a Transcreener Assay for Detection of AMP- and GMP-Producing Enzymes
Matt Staeben et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2010)
Novel Alexa Fluor-488 labeled antagonist of the A2A adenosine receptor: Application to a fluorescence polarization-based receptor binding assay
Miklos Kecskes et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Fluorescence Polarization/Anisotropy in Diagnostics and Imaging
David M. Jameson et al.
CHEMICAL REVIEWS (2010)
No Taste for Methyl: Methylation Sensitive Proteolysis in Drug Screening
Elisabeth-Maria Bissinger et al.
CHEMISTRY & BIOLOGY (2010)
Accessing Protein Methyltransferase and Demethylase Enzymology Using Microfluidic Capillary Electrophoresis
Tim J. Wigle et al.
CHEMISTRY & BIOLOGY (2010)
Structure-Based Drug Design and Optimization of Mannoside Bacterial FimH Antagonists
Zhenfu Han et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase
Adam Yasgar et al.
MOLECULAR BIOSYSTEMS (2010)
A chemiluminescence-based method for identification of histone lysine methyltransferase inhibitors
Amy M. Quinn et al.
MOLECULAR BIOSYSTEMS (2010)
The Year In G Protein-Coupled Receptor Research
Robert P. Millar et al.
MOLECULAR ENDOCRINOLOGY (2010)
Assay Strategies for the Discovery and Validation of Therapeutics Targeting Brugia pahangi Hsp90
Tony Taldone et al.
PLOS NEGLECTED TROPICAL DISEASES (2010)
Detection of the ATPase Activity of the Molecular Chaperones Hsp90 and Hsp72 Using the Transcreener™ AdP Assay Kit
Martin Rowlands et al.
JOURNAL OF BIOMOLECULAR SCREENING (2010)
High-affinity bisubstrate probe for fluorescence anisotropy binding/displacement assays with protein kinases PKA and ROCK
Angela Vaasa et al.
ANALYTICAL BIOCHEMISTRY (2009)
Characterization and Optimization of a Red-Shifted Fluorescence Polarization ADP Detection Assay
Karen M. Kleman-Leyer et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2009)
Development and Validation of a High-Density Fluorescence Polarization-Based Assay for the Trypanosoma RNA Triphosphatase TbCet1
Christophe Antczak et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2009)
Developments in fluorescent probes for receptor research
Marcello Leopoldo et al.
DRUG DISCOVERY TODAY (2009)
Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a
Feng Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Protein methyltransferases as a target class for drug discovery
Robert A. Copeland et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
From carbohydrate leads to glycomimetic drugs
Beat Ernst et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding
R. Z. Cer et al.
NUCLEIC ACIDS RESEARCH (2009)
Design, Synthesis, and Pharmacology of Fluorescently Labeled Analogs of Serotonin: Application to Screening of the 5-HT2C Receptor
Peter Cornelius et al.
JOURNAL OF BIOMOLECULAR SCREENING (2009)
Two G alpha(i1) Rate-Modifying Mutations Act in Concert to Allow Receptor-Independent, Steady-State Measurements of RGS Protein Activity
Thomas Zielinski et al.
JOURNAL OF BIOMOLECULAR SCREENING (2009)
A Novel Class of Small Molecule Inhibitors of Hsp90
Fang Yi et al.
ACS CHEMICAL BIOLOGY (2008)
Bright ideas for chemical biology
Luke D. Lavis et al.
ACS CHEMICAL BIOLOGY (2008)
Fluorescence polarization immunoassays and related methods for simple, high-throughput screening of small molecules
David S. Smith et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2008)
A high-throughput assay based on fluorescence polarization for inhibitors of the polo-box domain of polo-like kinase 1
Wolfgang Reindl et al.
ANALYTICAL BIOCHEMISTRY (2008)
Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosplioprotein interaction
Anton Simeonov et al.
ANALYTICAL BIOCHEMISTRY (2008)
Fluorescence anisotropy assay for the traceless kinetic analysis of protein digestion
Felix Cleemann et al.
ANALYTICAL CHEMISTRY (2008)
Inhibition of polo-like kinase 1 by blocking Polo-box domain-dependent protein-protein interactions
Wolfgang Reindl et al.
CHEMISTRY & BIOLOGY (2008)
A high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction
Adam J. Kimple et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2008)
Fluorescence spectroscopic profiling of compound libraries
Anton Simeonov et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Facile conversion of FP to TR-FRET assays using terbium chelates: Nuclear receptor competitive binding assays as examples
Kurt W. Vogel et al.
LETTERS IN DRUG DESIGN & DISCOVERY (2008)
Development, validation and implementation of immobilized metal affinity for phosphochemicals (IMAP)-based high-throughput screening assays for low-molecular-weight compound libraries
Elizabeth R. Sharlow et al.
NATURE PROTOCOLS (2008)
Cell-free assay of G-protein-coupled receptors using fluorescence polarization
Jessi Wildeson Jones et al.
JOURNAL OF BIOMOLECULAR SCREENING (2008)
Development of a homogeneous high-throughput live-cell G-protein-coupled receptor binding assay
Paul H. Lee et al.
JOURNAL OF BIOMOLECULAR SCREENING (2008)
Evaluating PI3 kinase isoforms using Transcreener™ ADP assays
Tony A. Klink et al.
JOURNAL OF BIOMOLECULAR SCREENING (2008)
Development of a Transcreener™ kinase assay for protein kinase A and demonstration of concordance of data with a filter-binding assay format
Karen L. Huss et al.
JOURNAL OF BIOMOLECULAR SCREENING (2007)
Inhibition of protein-protein interactions:: The discovery of druglike β-catenin inhibitors by combining virtual and biophysical screening
JY Trosset et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2006)
Screening in a spirit haunted world
Brian K. Shoichet
DRUG DISCOVERY TODAY (2006)
Carbohydrates as future anti-adhesion drugs for infectious diseases
N Sharon
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2006)
Adenosine receptors as therapeutic targets
KA Jacobson et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Transcreener™:: screening enzymes involved in covalent regulation
RG Lowery et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2006)
Aptamers as tools for target validation
M Blank et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2005)
Molecular aptamers for real-time protein-protein interaction study
ZH Cao et al.
CHEMISTRY-A EUROPEAN JOURNAL (2005)
Avidin plate assay system for enzymatic characterization of a histone lysine methyltransferase
H Gowher et al.
ANALYTICAL BIOCHEMISTRY (2005)
A coupled fluorescent assay for histone methyltransferases
E Collazo et al.
ANALYTICAL BIOCHEMISTRY (2005)
Protein-protein interactions and cancer: small molecules going in for the kill
M Arkin
CURRENT OPINION IN CHEMICAL BIOLOGY (2005)
Immobilized metal ion affinity-based fluorescence polarization (IMAP): Advances in kinase screening
JR Sportsman et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2004)
Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream
MR Arkin et al.
NATURE REVIEWS DRUG DISCOVERY (2004)
Cy3B™:: Improving the performance of cyanine dyes
M Cooper et al.
JOURNAL OF FLUORESCENCE (2004)
Use of red-shifted dyes in a fluorescence polarization AKT kinase assay for detection of biological activity in natural product extracts
TC Turek-Etienne et al.
JOURNAL OF BIOMOLECULAR SCREENING (2004)
Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization
Z Nikolovska-Coleska et al.
ANALYTICAL BIOCHEMISTRY (2004)
Fluorescence readouts in HTS: no gain without pain?
P Gribbon et al.
DRUG DISCOVERY TODAY (2003)
Identification and prediction of promiscuous aggregating inhibitors among known drugs
J Seidler et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Evaluation of compound interference in immobilized metal ion affinity-based fluorescence polarization detection with a four million member compound collection
JR Beasley et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2003)
Development and application of fluorescence polarization assays in drug discovery
TJ Burke et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2003)
Fluorescence polarization: Past, present and future
DM Jameson et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2003)
Extending the applicability of carboxyfluorescein in solid-phase synthesis
R Fischer et al.
BIOCONJUGATE CHEMISTRY (2003)
Evaluation of fluorescent compound interference in 4 fluorescence polarization assays: 2 kinases, 1 protease, and 1 phosphatase
TC Turek-Etienne et al.
JOURNAL OF BIOMOLECULAR SCREENING (2003)
Fluorescence polarization competition assay: The range of resolvable inhibitor potency is limited by the affinity of the fluorescent ligand
XY Huang
JOURNAL OF BIOMOLECULAR SCREENING (2003)
Modulation of protein-protein interactions with small organic molecules
T Berg
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
A non-radioactive method for the assay of many serine/threonine-specific protein kinases
H Ross et al.
BIOCHEMICAL JOURNAL (2002)
An evaluation of fluorescence polarization and lifetime discriminated polarization for high throughput screening of serine/threonine kinases
A Fowler et al.
ANALYTICAL BIOCHEMISTRY (2002)
A fluorescence polarization assay for cyclic nucleotide phosphodiesterases
W Huang et al.
JOURNAL OF BIOMOLECULAR SCREENING (2002)
Enzyme assays by fluorescence polarization in the presence of polyarginine: Study of kinase, phosphatase, and protease reactions
A Simeonov et al.
ANALYTICAL BIOCHEMISTRY (2002)
Stains, labels and detection strategies for nucleic acids assays
LJ Kricka
ANNALS OF CLINICAL BIOCHEMISTRY (2002)
Fluorescence polarization: Analysis of carbohydrate-protein interaction
K Kakehi et al.
ANALYTICAL BIOCHEMISTRY (2001)
Molecular characterization of the Escherichia coli FimH adhesin
MA Schembri et al.
JOURNAL OF INFECTIOUS DISEASES (2001)
Fluorescence polarization and anisotropy in high throughput screening: Perspectives and primer
JC Owicki
JOURNAL OF BIOMOLECULAR SCREENING (2000)
Impact of a red-shifted dye label for high throughput fluorescence polarization assays of G protein-coupled receptors
P Banks et al.
JOURNAL OF BIOMOLECULAR SCREENING (2000)
Oral bioavailability of digoxin is enhanced by talinolol: Evidence for involvement of intestinal P-glycoprotein
K Westphal et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2000)
Safe as mother's milk: Carbohydrates as future anti-adhesion drugs for bacterial diseases
N Sharon et al.
GLYCOCONJUGATE JOURNAL (2000)
Fluorescence polarization assays for high throughput screening of G protein-coupled receptors
P Banks et al.
JOURNAL OF BIOMOLECULAR SCREENING (2000)
Development of high throughput screening assays using fluorescence polarization: Nuclear receptor-ligand-binding and kinase/phosphatase assays
GJ Parker et al.
JOURNAL OF BIOMOLECULAR SCREENING (2000)
High throughput fluorescence polarization: A homogeneous alternative to radioligand binding for cell surface receptors
M Allen et al.
JOURNAL OF BIOMOLECULAR SCREENING (2000)
Detection of phosphopeptides by fluorescence polarization in the presence of cationic polyamino acids: application to kinase assays
J Coffin et al.
ANALYTICAL BIOCHEMISTRY (2000)
Antagonists of protein-protein interactions
AG Cochran
CHEMISTRY & BIOLOGY (2000)
Share Paper
