Related references
Note: Only part of the references are listed.Recent advances in bioluminescence resonance energy transfer technologies to study GPCR heteromerization
Mohammed A. Ayoub et al.
CURRENT OPINION IN PHARMACOLOGY (2010)
Cell surface delivery and structural re-organization by pharmacological chaperones of an oligomerization-defective α1b-adrenoceptor mutant demonstrates membrane targeting of GPCR oligomers
Meritxell Canals et al.
BIOCHEMICAL JOURNAL (2009)
Diversity in arrestin function
Ryan T. Kendall et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
Jeffrey J. Kovacs et al.
DEVELOPMENTAL CELL (2009)
Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation
Yang Han et al.
NATURE CHEMICAL BIOLOGY (2009)
Building a new conceptual framework for receptor heteromers
Sergi Ferre et al.
NATURE CHEMICAL BIOLOGY (2009)
Mu-opioid receptor beterooligomer formation with the dopamine D1 receptor as directly visualized in living cells
Jason R. Juhasz et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
G Protein Coupled Receptors as Drug Targets: The Role of β-Arrestins
Jasmin Dromey et al.
Endocrine Metabolic & Immune Disorders-Drug Targets (2008)
Demonstration of Improvements to the Bioluminescence Resonance Energy Transfer (BRET) Technology for the Monitoring of G Protein-Coupled Receptors in Live Cells
Martina Kocan et al.
JOURNAL OF BIOMOLECULAR SCREENING (2008)
Novel pharmacological applications of G-protein-coupled receptor-G protein fusions
Graeme Milligan et al.
CURRENT OPINION IN PHARMACOLOGY (2007)
Monitoring interactions between G-protein-coupled receptors and β-arrestins
K. D. G. Pfleger et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
Protean agonism at the dopamine D2 receptor:: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1, Gi2, and Gi3
J. Robert Lane et al.
MOLECULAR PHARMACOLOGY (2007)
The α1b-adrenoceptor exists as a higher-order oligomer:: Effective oligomerization is required for receptor maturation, surface delivery, and function
Juan F. Lopez-Gimenez et al.
MOLECULAR PHARMACOLOGY (2007)
Using ligand-induced conformational change to screen for compounds targeting G-protein-coupled receptors
Brian F. O'Dowd et al.
JOURNAL OF BIOMOLECULAR SCREENING (2007)
Uncovering the pharmacology of the G protein-coupled receptor GPR40: High apparent constitutive activity in guanosine 5'-O-(3-[S-35] thio) triphosphate binding studies reflects binding of an endogenous agonist
Leigh A. Stoddart et al.
MOLECULAR PHARMACOLOGY (2007)
Functional selectivity and classical concepts of quantitative pharmacology
Jonathan D. Urban et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Extended bioluminescence resonance energy transfer (eBRET) for monitoring prolonged protein-protein interactions in live cells
Kevin D. G. Pfleger et al.
CELLULAR SIGNALLING (2006)
The G12 family of G proteins as a reporter of thromboxane A2 receptor activity
L Zhang et al.
MOLECULAR PHARMACOLOGY (2006)
Bring your own G protein
JD Hildebrandt
MOLECULAR PHARMACOLOGY (2006)
Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET)
KDG Pfleger et al.
NATURE METHODS (2006)
Interactions between the Mas-related receptors MrgD and MrgE alter signalling and trafficking of MrgD
S Milasta et al.
MOLECULAR PHARMACOLOGY (2006)
Bioluminescence resonance energy transfer (BRET) for the real-time detection of protein-protein interactions
Kevin D. G. Pfleger et al.
NATURE PROTOCOLS (2006)
The structural basis of arrestin-mediated regulation of G-protein-coupled receptors
Vsevolod V. Gurevich et al.
PHARMACOLOGY & THERAPEUTICS (2006)
Structural basis of antigen mimicry in a clinically relevant melanoma antigen system
CC Chung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Crosstalk in G protein-coupled receptors: Changes at the transmembrane homodimer interface determine activation
W Guo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Dopamine receptor oligomerization visualized in living cells
BF O'Dowd et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The CXCR1 and CXCR2 receptors form constitutive homo- and heterodimers selectively and with equal apparent affinities
S Wilson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Evaluation of the InteraX™ System technology in a high-throughput screening environment
FH Büttner et al.
JOURNAL OF BIOMOLECULAR SCREENING (2005)
Oligomerization of the fifth transmembrane domain from the adenosine A2A receptor
D Thévenin et al.
PROTEIN SCIENCE (2005)
High-throughput screening of G protein-coupled receptor antagonists using a bioluminescence resonance energy transfer 1-based β-arrestin2 recruitment assay
FF Hamdan et al.
JOURNAL OF BIOMOLECULAR SCREENING (2005)
A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers
M Waldhoer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Multiple signaling states of G-protein-coupled receptors
DM Perez et al.
PHARMACOLOGICAL REVIEWS (2005)
Methods to monitor the quaternary structure of G protein-coupled receptors
G Milligan et al.
FEBS JOURNAL (2005)
Transduction of receptor signals by β-arrestins
RJ Leftowitz et al.
SCIENCE (2005)
Activation of an alpha(2A)-adrenoceptor-G alpha(o1), fusion protein dynamically regulates the palmitoylation status of the G protein but not of the receptor
E Barclay et al.
BIOCHEMICAL JOURNAL (2005)
Applications of bioluminescence- and fluorescence resonance energy transfer to drug discovery at G protein-coupled receptors
G Milligan
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2004)
Agonist-independent nuclear localization of the apelin, angiotensin AT1, and bradykinin B2 receptors
DK Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Dopamine D1 and D2 receptor co-activation generates a novel phospholipase C-mediated calcium signal
SP Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Hetero-oligomerization between β2-and β3-adrenergic receptors generates a β-adrenergic signaling unit with distinct functional properties
A Breit et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
G protein-coupled receptor fusion proteins in drug discovery
G Milligan et al.
CURRENT PHARMACEUTICAL DESIGN (2004)
Multiple interactions between transmembrane helices generate the oligomeric α1b-adrenoceptor
JJ Carrillo et al.
MOLECULAR PHARMACOLOGY (2004)
Domain swapping in the human histamine H1 receptor
RA Bakker et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Oligomerization, biogenesis, and signaling is promoted by a glycophorin A-like dimerization motif in transmembrane domain 1 of a yeast G protein-coupled receptor
MC Overton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of surrogate ligands, for orphan G protein-coupled receptors
S Takeda et al.
LIFE SCIENCES (2003)
Dimers of class A G protein-coupled receptors function via agonist-mediated trans-activation of associated G proteins
JJ Carrillo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Oligomerization of the α1a- and α1b-adrenergic receptor subtypes -: Potential implications in receptor internalization
L Stanasila et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Properties of Arg389-β1-adrenoceptor-Gsα fusion proteins:: Comparison with Gly389-β1-adrenoceptor-Gsα fusion proteins
K Wenzel-Seifert et al.
RECEPTORS & CHANNELS (2003)
Phosphorylation-independent desensitization of GABAB receptor by GRK4
J Perroy et al.
EMBO JOURNAL (2003)
Hypersensitization of the orexin 1 receptor by the CB1 receptor -: Evidence for cross-talk blocked by the specific CB1 antagonist, SR141716
S Hilairet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes
Y Liang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Heterodimerization of α2A- and β1-adrenergic receptors
JG Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling
SK Shenoy et al.
BIOCHEMICAL JOURNAL (2003)
Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes -: Differential regulation of β-arrestins 1 and 2
AC Hanyaloglu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Enzyme fragment complementation: A flexible high throughput screening assay technology
RM Eglen
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2002)
G-protein-coupled receptor oligomerization and its potential for drug discovery
SR George et al.
NATURE REVIEWS DRUG DISCOVERY (2002)
Identification of a novel human eicosanoid receptor coupled to Gi/o
T Hosoi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Agonist-dependent dissociation of oligomeric complexes of G protein-coupled cholecystokinin receptors demonstrated in living cells using bioluminescence resonance energy transfer
ZJ Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Lipid-facing correlated mutations and dimerization in G-protein coupled receptors
PR Gouldson et al.
PROTEIN ENGINEERING (2001)
Increased AT1 receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness
S AbdAlla et al.
NATURE MEDICINE (2001)
Constitutive and agonist-dependent homo-oligomerization of the thyrotropin-releasing hormone receptor - Detection in living cells using bioluminescence resonance energy transfer
KM Kroeger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Naturally occurring deletional mutation in the C-terminal cytoplasmic tail of CCR5 affects surface trafficking of CCR5
T Shioda et al.
JOURNAL OF VIROLOGY (2001)
Inverse, protean, and ligand-selective agonism: matters of receptor conformation
T Kenakin
FASEB JOURNAL (2001)
Oligomerization of μ- and δ-opioid receptors -: Generation of novel functional properties
SR George et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Differential affinities of visual arrestin, βarrestin1, and βarrestin2 for G protein-coupled receptors delineate two major classes of receptors
RH Oakley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Sorting proteins to their target membranes
D Brown et al.
KIDNEY INTERNATIONAL (2000)
Insights into ligand pharmacology using receptor-G-protein fusion proteins
G Milligan
TRENDS IN PHARMACOLOGICAL SCIENCES (2000)
High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation
DH Juers et al.
PROTEIN SCIENCE (2000)