Related references
Note: Only part of the references are listed.Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR
Richard M. Angell et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode
Richard M. Angell et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
A quantitative analysis of kinase inhibitor selectivity
Mazen W. Karaman et al.
NATURE BIOTECHNOLOGY (2008)
A novel substrate mimetic inhibitor of PKB/Akt inhibits prostate cancer tumor growth in mice by blocking the PKB pathway
Pninit Litman et al.
BIOCHEMISTRY (2007)
Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase
I. Wayne Cheney et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Structures of lung cancer-derived EGFR mutants and inhibitor complexes: Mechanism of activation and insights into differential inhibitor sensitivity
Cai-Hong Yun et al.
CANCER CELL (2007)
Molecular recognition of protein kinase binding pockets for design of potent and selective kinase inhibitors
Jeffrey Jie-Lou Liao
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Opinion - Angiogenesis: an organizing principle for drug discovery?
Judah Folkman
NATURE REVIEWS DRUG DISCOVERY (2007)
A general strategy for creating Inactive-conformation Abl inhibitors
Barun Okram et al.
CHEMISTRY & BIOLOGY (2006)
Rational design of inhibitors that bind to inactive kinase conformations
Y Liu et al.
NATURE CHEMICAL BIOLOGY (2006)
Inhibitors of epidermal growth factor receptor tyrosine kinase: Novel C-5 substituted anilinoquinazolines designed to target the ribose pocket
P Ballard et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
NMR characterization of kinase p38 dynamics in free and ligand-bound forms
M Vogtherr et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
Prevention of MKK6-dependent activation by binding to p38α MAP kinase
JE Sullivan et al.
BIOCHEMISTRY (2005)
Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases
TA Carter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002
MD Jacobs et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A small molecule-kinase interaction map for clinical kinase inhibitors
MA Fabian et al.
NATURE BIOTECHNOLOGY (2005)
Interactions of LY333531 and other bisindolyl maleimide inhibitors with PDK1
D Komander et al.
STRUCTURE (2004)
Regulation of protein kinases: Controlling activity through activation segment conformation
B Nolen et al.
MOLECULAR CELL (2004)
Regulation of the C-Abl and Bcr-Abl tyrosine kinases
O Hantschel et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Living with or without cyclins and cyclin-dependent kinases
CJ Sherr et al.
GENES & DEVELOPMENT (2004)
Crystal structures of the phosphorylated and unphosphorylated kinase domains of the Cdc42-associated tyrosine kinase ACK1
JC Lougheed et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Protein tyrosine kinases Src and Csk: a tail's tale
PA Cole et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2003)
Structural basis for p38α MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity
CE Fitzgerald et al.
NATURE STRUCTURAL BIOLOGY (2003)
The structure of JNK3 in complex with small molecule inhibitors: Structural basis for potency and selectivity
G Scapin et al.
CHEMISTRY & BIOLOGY (2003)
The protein kinase complement of the human genome
G Manning et al.
SCIENCE (2002)
Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor
J Stamos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The conformational plasticity of protein kinases
M Huse et al.
CELL (2002)
Protein kinases - the major drug targets of the twenty-first century?
P Cohen
NATURE REVIEWS DRUG DISCOVERY (2002)
Designing bisubstrate analog inhibitors for protein kinases
K Parang et al.
PHARMACOLOGY & THERAPEUTICS (2002)
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
ME Gorre et al.
SCIENCE (2001)
Quinazolines as cyclin dependent kinase inhibitors
TM Sielecki et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2001)
Inhibition of cyclin-dependent kinases, GSK-3 beta and CK1 by hymenialdisine, a marine sponge constituent
L Meijer et al.
CHEMISTRY & BIOLOGY (2000)
Share Paper
