Related references
Note: Only part of the references are listed.Engineered Soluble Monomeric IgG1 CH3 Domain GENERATION, MECHANISMS OF FUNCTION, AND IMPLICATIONS FOR DESIGN OF BIOLOGICAL THERAPEUTICS
Tianlei Ying et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Defining the Interaction of HIV-1 with the Mucosal Barriers of the Female Reproductive Tract
Ann M. Carias et al.
JOURNAL OF VIROLOGY (2013)
Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges
James M. Smith et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
In Vitro Resistance Profile of the Candidate HIV-1 Microbicide Drug Dapivirine
Susan M. Schader et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
A novel vaginal microbicide containing the rationally designed anti-HIV compound HI-443 (N′-[2-(2-thiophene)ethyl]-N′-[2-(5-bromopyridyl)] thiourea])
Osmond J. D'Cruz et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2012)
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
Florian Klein et al.
NATURE (2012)
An Intravaginal Ring That Releases the NNRTI MIV-150 Reduces SHIV Transmission in Macaques
Rachel Singer et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Animal models of antiretroviral prophylaxis for HIV prevention
J. Gerardo Garcia-Lerma et al.
CURRENT OPINION IN HIV AND AIDS (2012)
Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women
Salim S. Abdool Karim et al.
AIDS (2011)
Early Events in Sexual Transmission of HIV and SIV and Opportunities for Interventions
Ashley T. Haase
ANNUAL REVIEW OF MEDICINE, VOL 62, 2011 (2011)
Cell-Free HIV-1 Virucidal Action by Modified Peptide Triazole Inhibitors of Env gp120
Arangassery R. Bastian et al.
CHEMMEDCHEM (2011)
Tenofovir renal proximal tubular toxicity is regulated By OAT1 and MRP4 transporters
James J. Kohler et al.
LABORATORY INVESTIGATION (2011)
Broad neutralization coverage of HIV by multiple highly potent antibodies
Laura M. Walker et al.
NATURE (2011)
A Phase I Randomized Placebo Controlled Trial of the Safety of 3% SPL7013 Gel (VivaGel®) in Healthy Young Women Administered Twice Daily for 14 Days
Craig R. Cohen et al.
PLOS ONE (2011)
An Antiretroviral/Zinc Combination Gel Provides 24 Hours of Complete Protection against Vaginal SHIV Infection in Macaques
Jessica Kenney et al.
PLOS ONE (2011)
K70Q Adds High-Level Tenofovir Resistance to Q151M Complex HIV Reverse Transcriptase through the Enhanced Discrimination Mechanism
Atsuko Hachiya et al.
PLOS ONE (2011)
An Aptamer-siRNA Chimera Suppresses HIV-1 Viral Loads and Protects from Helper CD4+ T Cell Decline in Humanized Mice
Charles Preston Neff et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Pharmacokinetic Assessment of Dapivirine Vaginal Microbicide Gel in Healthy, HIV-Negative Women
Annalene M. Nel et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2010)
Advances in microbicide vaginal rings
R. Karl Malcolm et al.
ANTIVIRAL RESEARCH (2010)
Protection of Rhesus Macaques from Vaginal Infection by Vaginally Delivered Maraviroc, an Inhibitor of HIV-1 Entry via the CCR5 Co-Receptor
Ronald S. Veazey et al.
JOURNAL OF INFECTIOUS DISEASES (2010)
Structure Activity Relationship of Dendrimer Microbicides with Dual Action Antiviral Activity
David Tyssen et al.
PLOS ONE (2010)
Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
Quarraisha Abdool Karim et al.
SCIENCE (2010)
Protective properties of non-nucleoside reverse transcriptase inhibitor (MC1220) incorporated into liposome against intravaginal challenge of Rhesus Macaques with RT-SHIV
Melanie Caron et al.
VIROLOGY (2010)
PVP-coated silver nanoparticles block the transmission of cell-free and cell-associated HIV-1 in human cervical culture
Humberto H Lara et al.
JOURNAL OF NANOBIOTECHNOLOGY (2010)
Safety and Availability of Dapivirine (TMC120) Delivered from an Intravaginal Ring
J. Romano et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2009)
Inhibition of Human Immunodeficiency Virus Type 1 Infection by the Candidate Microbicide Dapivirine, a Nonnucleoside Reverse Transcriptase Inhibitor
P. Fletcher et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Safety and Pharmacokinetics of Dapivirine Delivery From Matrix and Reservoir Intravaginal Rings to HIV-Negative Women
Annalene Nel et al.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2009)
Structural Basis for the Role of the K65R Mutation in HIV-1 Reverse Transcriptase Polymerization, Excision Antagonism, and Tenofovir Resistance
Kalyan Das et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Low Bone Mineral Density, Renal Dysfunction, and Fracture Risk in HIV Infection: A Cross-Sectional Study
Alexandra Calmy et al.
JOURNAL OF INFECTIOUS DISEASES (2009)
Tenofovir renal toxicity targets mitochondria of renal proximal tubules
James J. Kohler et al.
LABORATORY INVESTIGATION (2009)
Nano and Microtechnologies for the Delivery of Oligonucleotides with Gene Silencing Properties
Giuseppe De Rosa et al.
MOLECULES (2009)
Targeted Delivery of PSC-RANTES for HIV-1 Prevention using Biodegradable Nanoparticles
Anthony S. Ham et al.
PHARMACEUTICAL RESEARCH (2009)
Broadly Neutralizing Human Anti-HIV Antibody 2G12 Is Effective in Protection against Mucosal SHIV Challenge Even at Low Serum Neutralizing Titers
Ann J. Hessell et al.
PLOS PATHOGENS (2009)
Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission
Per Johan Masse et al.
ANNUAL REVIEW OF MEDICINE (2008)
T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice
Priti Kumar et al.
CELL (2008)
Genome-Scale RNAi Screen for Host Factors Required for HIV Replication
Honglin Zhou et al.
CELL HOST & MICROBE (2008)
Inhibition of HIV fusion with multivalent gold nanoparticles
Mary-Catherine Bowman et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial
Stephanie Skoler-Karpoff et al.
LANCET (2008)
Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy
Jiehua Zhou et al.
MOLECULAR THERAPY (2008)
Mucosal delivery of therapeutic and prophylactic molecules using lactic acid bacteria
Jerry M. Wells et al.
NATURE REVIEWS MICROBIOLOGY (2008)
Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission
Lut Van Damme et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
SAVVY Vaginal Gel (C31G) for Prevention of HIV Infection: A Randomized Controlled Trial in Nigeria
Paul J. Feldblum et al.
PLOS ONE (2008)
Identification of host proteins required for HIV infection through a functional genomic screen
Abraham L. Brass et al.
SCIENCE (2008)
Rational design of novel HIV-1 entry inhibitors by RANTES engineering
Luca Vangelista et al.
VACCINE (2008)
Setting the stage: host invasion by HIV
Florian Hladik et al.
NATURE REVIEWS IMMUNOLOGY (2008)
SAVVY® (C31G) Gel for Prevention of HIV infection in Women: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Ghana
Leigh Peterson et al.
PLOS ONE (2007)
RNAi therapeutics: Principles, prospects and challenges
Lars Aagaard et al.
ADVANCED DRUG DELIVERY REVIEWS (2007)
Chemoprophylaxis with tenofovir disoproxil fumarate provided partial protection against infection with simian human immunodeficiency virus in macaques given multiple virus challenges
Shambavi Subbarao et al.
JOURNAL OF INFECTIOUS DISEASES (2006)
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
James O. McNamara et al.
NATURE BIOTECHNOLOGY (2006)
Novel tight binding PETT, HEPT and DABO-based non-nucleoside inhibitors of HIV-1 reverse transcriptase
Osmond J. D'Cruz et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2006)
Bioengineering lactic acid bacteria to secrete the HIV-1 virucide cyanovirin
O Pusch et al.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2005)
Comparison of the mucoadhesive properties of various polymers
V Grabovac et al.
ADVANCED DRUG DELIVERY REVIEWS (2005)
SPL7013 gel as a topical microbicide for prevention of vaginal transmission of SHIV89.6P in macaques
YH Jiang et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2005)
Conceival, a novel noncontraceptive vaginal vehicle for lipophilic microbicides
OJ D'Cruz et al.
AAPS PHARMSCITECH (2005)
Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion, after residue 69 and multiple thymidine analog-associated mutations
KL White et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Stampidine is a potential nonspermicidal broad-spectrum anti-human immunodeficiency virus microbicide
OJ D'Cruz et al.
FERTILITY AND STERILITY (2004)
PHI-443: A novel noncontraceptive broad-spectrum anti-human immunodeficiency virus microbicide
OJ D'Cruz et al.
BIOLOGY OF REPRODUCTION (2004)
Clinical development of microbicides for the prevention of HIV infection
OJ D'Cruz et al.
CURRENT PHARMACEUTICAL DESIGN (2004)
Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5
MM Lederman et al.
SCIENCE (2004)
Neutralization of infectivity of diverse R5 clinical isolates of human immunodeficiency virus type 1 by gp120-binding 2′F-RNA aptamers
M Khati et al.
JOURNAL OF VIROLOGY (2003)
Influence of silicone elastomer solubility and diffusivity on the in vitro release of drugs from intravaginal rings
K Malcolm et al.
JOURNAL OF CONTROLLED RELEASE (2003)
Novel therapies based on mechanisms of HIV-1 cell entry
JM Kilby et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
In vivo Antiretroviral activity of stampidine in chronically feline immunodeficiency virus-infected cats
FM Uckun et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
Pre-clinical safety evaluation of novel nucleoside analogue-based dual-function microbicides (WHI-05 and WHI-07)
OJ D'Cruz et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2002)
Metabolism of stavudine-5′-[p-bromophenyl methoxyalaninyl phosphate], stampidine, in mice, dogs, and cats
CL Chen et al.
DRUG METABOLISM AND DISPOSITION (2002)
In vivo toxicity, pharmacokinetics, and anti-human immunodeficiency virus activity of stavudine-5′-(p-bromophenyl methoxyalaninyl phosphate) (stampidine) in mice
FM Uckun et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
Stampidine is a potent inhibitor of zidovudine- and nucleoside analog reverse transcriptase inhibitor-resistant primary clinical human immunodeficiency virus type 1 isolates with thymidine analog mutations
FM Uckun et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro
PWHI Parren et al.
JOURNAL OF VIROLOGY (2001)
Gel-microemulsions as vaginal spermicides and intravaginal drug delivery vehicles
OJ D'Cruz et al.
CONTRACEPTION (2001)
Microemulsion-based media as novel drug delivery systems
MJ Lawrence et al.
ADVANCED DRUG DELIVERY REVIEWS (2000)