Related references
Note: Only part of the references are listed.Human Hemato-Lymphoid System Mice: Current Use and Future Potential for Medicine
Anthony Rongvaux et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)
Potent in vitro and in vivo activity of sorafenib in multiple myeloma: induction of cell death, CD138-downregulation and inhibition of migration through actin depolymerization
Josefina Udi et al.
BRITISH JOURNAL OF HAEMATOLOGY (2013)
A germline-competent embryonic stem cell line from NOD.Cg-Prkdc scid Il2rg tm1Wjl /SzJ (NSG) mice
Carlisle P. Landel et al.
TRANSGENIC RESEARCH (2013)
e-Blood Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma
Richard W. J. Groen et al.
BLOOD (2012)
Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features
Abdel Kareem Azab et al.
BLOOD (2012)
Drug response in a genetically engineered mouse model of multiple myeloma is predictive of clinical efficacy
Marta Chesi et al.
BLOOD (2012)
Synthetic miR-34a Mimics as a Novel Therapeutic Agent for Multiple Myeloma: In Vitro and In Vivo Evidence
Maria T. Di Martino et al.
CLINICAL CANCER RESEARCH (2012)
Natural killer cell lines preferentially kill clonogenic multiple myeloma cells and decrease myeloma engraftment in a bioluminescent xenograft mouse model
Brenna E. Swift et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2012)
Highly activated and expanded natural killer cells for multiple myeloma immunotherapy
Tarun K. Garg et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2012)
Anti-tumor activity of a B-cell receptor-targeted peptide in a novel disseminated lymphoma xenograft model
Claudia Wehr et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Therapeutic effects of intrabone and systemic mesenchymal stem cell cytotherapy on myeloma bone disease and tumor growth
Xin Li et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2012)
Challenging the current approaches to multiple myeloma- and other cancer-related bone diseases: from bisphosphonates to targeted therapy
Martina Kleber et al.
LEUKEMIA & LYMPHOMA (2012)
2011 in reflection
Asher Mullard
NATURE REVIEWS DRUG DISCOVERY (2012)
Optical Imaging of Disseminated Leukemia Models in Mice with Near-Infrared Probe Conjugated to a Monoclonal Antibody
Sabrina Pesnel et al.
PLOS ONE (2012)
FXR Controls the Tumor Suppressor NDRG2 and FXR Agonists Reduce Liver Tumor Growth and Metastasis in an Orthotopic Mouse Xenograft Model
Ulrich Deuschle et al.
PLOS ONE (2012)
Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications
Jana Jakubikova et al.
BLOOD (2011)
Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide
Yuan Xiao Zhu et al.
BLOOD (2011)
Diversity of Human Leukemia Xenograft Mouse Models: Implications for Disease Biology
Lueder Hinrich Meyer et al.
CANCER RESEARCH (2011)
A Blueprint for Advancing Genetics-Based Cancer Therapy
William R. Sellers
CELL (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Emerging Therapies Targeting Tumor Vasculature in Multiple Myeloma and other Hematologic and Solid Malignancies
K. Podar et al.
CURRENT CANCER DRUG TARGETS (2011)
Leukemia Stem Cells and Microenvironment: Biology and Therapeutic Targeting
Marina Y. Konopleva et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
A unique three-dimensional SCID-polymeric scaffold (SCID-synth-hu) model for in vivo expansion of human primary multiple myeloma cells
T. Calimeri et al.
LEUKEMIA (2011)
Early and mature endothelial progenitors and VEGFR2+-cells in multiple myeloma: Association with disease characteristics and variation in different cell compartments
Josefina Udi et al.
LEUKEMIA RESEARCH (2011)
ANIMAL MODELS Towards a myeloma mouse
Sarah Deweerdt
NATURE (2011)
Sensitive Dual Color In Vivo Bioluminescence Imaging Using a New Red Codon Optimized Firefly Luciferase and a Green Click Beetle Luciferase
Laura Mezzanotte et al.
PLOS ONE (2011)
Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment
Faiyaz Notta et al.
SCIENCE (2011)
Human Placenta-Derived Adherent Cells Prevent Bone loss, Stimulate Bone formation, and Suppress Growth of Multiple Myeloma in Bone
Xin Li et al.
STEM CELLS (2011)
Hallmarks of cancer: Interactions with the tumor stroma
Kristian Pietras et al.
EXPERIMENTAL CELL RESEARCH (2010)
Growth and differentiation of bone marrow stromal cells on biodegradable polymer scaffolds: An in vitro study
Ying Xue et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2010)
Of Mice and Humans: Are They the Same?-Implications in Cancer Translational Research
Marion de Jong et al.
JOURNAL OF NUCLEAR MEDICINE (2010)
Osteoblastogenesis and tumor growth in myeloma
Shmuel Yaccoby
LEUKEMIA & LYMPHOMA (2010)
European Myeloma Network: the 3rd Trialist Forum Consensus Statement from the European experts meeting on multiple myeloma
Monika Engelhardt et al.
LEUKEMIA & LYMPHOMA (2010)
Telomerase Inhibition Targets Clonogenic Multiple Myeloma Cells through Telomere Length-Dependent and Independent Mechanisms
Sarah K. Brennan et al.
PLOS ONE (2010)
Humanized nonobese diabetic-scid IL2rγnull mice are susceptible to lethal Salmonella Typhi infection
Stephen J. Libby et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents
Sreenath V. Sharma et al.
NATURE REVIEWS CANCER (2010)
The ephrinB2/EphB4 axis is dysregulated in osteoprogenitors from myeloma patients and its activation affects myeloma bone disease and tumor growth
Angela Pennisi et al.
BLOOD (2009)
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy
Abdel Kareem Azab et al.
BLOOD (2009)
Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma
Mariateresa Fulciniti et al.
BLOOD (2009)
The leukemic stem cell niche: current concepts and therapeutic opportunities
Steven W. Lane et al.
BLOOD (2009)
β1 Integrin Adhesion Enhances IL-6-Mediated STAT3 Signaling in Myeloma Cells: Implications for Microenvironment Influence on Tumor Survival and Proliferation
Kenneth H. Shain et al.
CANCER RESEARCH (2009)
A High-Affinity Fully Human Anti-IL-6 mAb, 1339, for the Treatment of Multiple Myeloma
Mariateresa Fulciniti et al.
CLINICAL CANCER RESEARCH (2009)
A comparison of cytokine production in 2-dimensional and 3-dimensional cultures of bone marrow stromal cells of muliple myeloma patients in response to RPMI8226 myeloma cells
Barbara Zdzisinska et al.
FOLIA HISTOCHEMICA ET CYTOBIOLOGICA (2009)
Targeted Disruption of the CXCL12/CXCR4 Axis Inhibits Osteolysis in a Murine Model of Myeloma-Associated Bone Loss
Peter Diamond et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2009)
Criteria for diagnosis, staging, risk stratification and response assessment of multiple myeloma
R. A. Kyle et al.
LEUKEMIA (2009)
A unique three-dimensional model for evaluating the impact of therapy on multiple myeloma
Julia Kirshner et al.
BLOOD (2008)
Role of decorin in the antimyeloma effects of osteoblasts
Xin Li et al.
BLOOD (2008)
Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth
Ya-Wei Qiang et al.
BLOOD (2008)
AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies
Marta Chesi et al.
CANCER CELL (2008)
An update on the xenograft and mouse models suitable for investigating new therapeutic compounds for the treatment of B-cell malignancies
Paolo Macor et al.
CURRENT PHARMACEUTICAL DESIGN (2008)
Increased regulatory versus effector T cell development is associated with thymus atrophy in mouse models of multiple myeloma
Ayelet Laronne-Bar-On et al.
JOURNAL OF IMMUNOLOGY (2008)
The bone marrow niche: habitat to hematopoietic and mesenchymal stem cells, and unwitting host to molecular parasites
Y. Shiozawa et al.
LEUKEMIA (2008)
Extravasation and homing mechanisms in multiple myeloma
Isabelle Vande Broek et al.
CLINICAL & EXPERIMENTAL METASTASIS (2008)
Characterization of in vitro growth of multiple myeloma cells
Mihaela Zlei et al.
EXPERIMENTAL HEMATOLOGY (2007)
The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy
Yang Yang et al.
BLOOD (2007)
Wnt3/RhoA/ROCK signaling pathway is involved in adhesion-mediated drug resistance of multiple myeloma in an autocrine mechanism
Masayoshi Kobune et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Hypoxia-inducible factors, stem cells, and cancer
Brian Keith et al.
CELL (2007)
Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo
Shmuel Yaccoby et al.
BLOOD (2007)
A study of the biological receptor activator of nuclear factor-κB ligand inhibitor, denosumab, in patients with multiple myeloma or bone metastases from breast cancer
JJ Body et al.
CLINICAL CANCER RESEARCH (2006)
Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation
N Giuliani et al.
BLOOD (2005)
Molecular pathogenesis and a consequent classification of multiple myeloma
PL Bergsagel et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells
M Burger et al.
BLOOD (2005)
Human short-term repopulating stem cells are efficiently detected following intrafemoral transplantation into NOD/SCID recipients depleted of CD122+ cells
JL McKenzie et al.
BLOOD (2005)
Multiple drug resistance in cancer revisited: The cancer stem cell hypothesis
VS Donnenberg et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2005)
A clinically relevant SCID-hu in vivo model of human multiple myeloma
P Tassone et al.
BLOOD (2005)
Phenotypic characterization of the human myeloma cell growth fraction
N Robillard et al.
BLOOD (2005)
The SCID-rab model:: a novel in vivo system for primary human myeloma demonstrating growth of CD138-expressing malignant cells
K Yata et al.
LEUKEMIA (2004)
Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: a vicious cycle between bone destruction and myeloma expansion
M Abe et al.
BLOOD (2004)
Evaluation of mineralized collagen and alpha-tricalcium phosphate as scaffolds for tissue engineering of bone using human mesenchymal stem cells
P Niemeyer et al.
CELLS TISSUES ORGANS (2004)
IL-6 regulates CD44 cell surface expression on human myeloma cells
T Vincent et al.
LEUKEMIA (2004)
Antimyeloma efficacy of thalidomide in the SCID-hu model
S Yaccoby et al.
BLOOD (2002)
NOD/SCID/γcnull mouse:: an excellent recipient mouse model for engraftment of human cells
M Ito et al.
BLOOD (2002)
The role of tumor necrosis factor α in the pathophysiology of human multiple myeloma:: therapeutic applications
T Hideshima et al.
ONCOGENE (2001)
Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials
JI Johnson et al.
BRITISH JOURNAL OF CANCER (2001)
Chemokine stromal cell-derived factor-1α modulates VLA-4 integrin-mediated multiple myeloma cell adhesion to CS-1/fibronectin and VCAM-1
F Sanz-Rodríguez et al.
BLOOD (2001)
Share Paper
