Journal
EXPERT OPINION ON BIOLOGICAL THERAPY
Volume 13, Issue 1, Pages 77-84Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1517/14712598.2013.727391
Keywords
angiogenesis; colon cancer; microRNA; miR-107; miR-145; miR-194; miR-27a; miR-802
Funding
- National Natural Scientific Foundation of China [81100714, 81171923]
- Foundation of Shaanxi Province Science and Technology Research [2012KJXX-20]
- Top PhD Foundation of China [201075]
Ask authors/readers for more resources
Introduction: Angiogenesis, for its fundamental role in cancer growth and metastasis, has become an appealing target in cancer therapy. A number of angiogenesis-related microRNAs (miRNAs) are under investigation and they can affect the cancerous phenotype of malignant cells. Areas covered: The authors review the recent advances in angiogenesis-related miRNAs in human colon cancer. They also envisage future developments toward potential miRNA-based applications to cancer treatment. Expert opinion: Angiogenesis-related miRNAs may reasonably be considered as a valuable cancer therapeutic tool. More investigations should be performed to promote therapeutic-clinical research of miRNAs in patients with colon cancer.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available