Journal
EXPERT OPINION ON BIOLOGICAL THERAPY
Volume 8, Issue 5, Pages 643-655Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1517/14712598.8.5.643
Keywords
chronic inflammatory demyelinating polyradiculoneuropathy; CIDP; immunotherapy; polyneuropathy; treatment
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Background: chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune-mediated disease. Current treatments are aimed at modulating the immune response to achieve remission and maintain functional status. However, many patients fail to make a long-term recovery with current treatments. Objectives: to review the literature on immunotherapy for CIDP. Methods: We used the Search Strategy of the Cochrane Neuromuscular Disease Review Group to search Medline and Embase. Randomised and non-randomised studies examining the effects of any therapeutic agent in patients with CIDP were selected. The references of relevant articles were scanned to identify additional reports of interest. Results/conclusion: An overview of the different treatments for CIDP is provided. Emphasis has been placed on evidence from randomised controlled trials but open non-randomised studies are discussed if appropriate. We include a treatment algorithm and provide our views on current treatments, ongoing trials and possible directions for further research.
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