Journal
EXPERIMENTAL PHYSIOLOGY
Volume 96, Issue 1, Pages 40-50Publisher
WILEY-BLACKWELL
DOI: 10.1113/expphysiol.2010.052597
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Funding
- Wellcome Trust
- British Heart Foundation
- Biotechnology and Biological Sciences Research Council
- Russian Academy of Sciences
- British Heart Foundation [PG/09/064/27886] Funding Source: researchfish
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We briefly review the current literature where optogenetics has been used to study various aspects of astrocyte physiology in vitro and in vivo. This includes both genetically engineered Ca2+ sensors and effector proteins, such as channelrhodopsin. We demonstrate how the ability to target astrocytes with cell-specific viral vectors to express optogenetic constructs helped to unravel some previously unsuspected roles of these inconspicuous cells.
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