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Serum microRNAs as a novel class of biomarkers a comprehensive review of the literature

Journal

EXPERIMENTAL HEMATOLOGY
Volume 38, Issue 12, Pages 1126-1130

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.exphem.2010.10.004

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Recently, expression patterns of microRNAs in body fluids underscored their potential as noninvasive biomarkers for various diseases Here we summarize the current works describing microRNAs in blood cells or serum as biomarkers and the applied methodologies of small RNA purification and detection Future challenges and the required research relating to optimization of working with microRNAs in serum will also be discussed (C) 2010 ISEH Society for Hematology and Stem Cells Published by Elsevier Inc

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