Journal
EXPERIMENTAL CELL RESEARCH
Volume 319, Issue 2, Pages 147-151Publisher
ELSEVIER INC
DOI: 10.1016/j.yexcr.2012.08.009
Keywords
Primary cilia; Actin; Vesicle
Categories
Funding
- National Basic Research Program of China [2012CB945003, 2010CB912102]
- National Science Foundation of China [30971430]
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Cilia dysfunction leads to developmental defects and also a spectrum of human diseases termed ciliopathies. The actin cytoskeleton is a highly dynamic network and involved in many important biological processes, such as cell migration and membrane trafficking. Recently, actin dynamics has been shown to play a critical role in ciliogenesis. This review summarizes these results and provides insight into possible mechanisms. (c) 2012 Elsevier Inc. All rights reserved.
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