Journal
EXPERIMENTAL CELL RESEARCH
Volume 316, Issue 18, Pages 3028-3033Publisher
ELSEVIER INC
DOI: 10.1016/j.yexcr.2010.05.002
Keywords
Notch; Muscle
Categories
Funding
- NIGMS NIH HHS [T32 GM008216] Funding Source: Medline
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Notch signaling has emerged as a key player in skeletal muscle development and regeneration. Simply stated, Notch signaling inhibits differentiation. Accordingly, fine-tuning the pathway is essential for proper muscle homeostasis. This review will address various aspects of Notch signaling, including our current views of the core pathway, its effects in muscle, its interactions with other signaling pathways, and its relationship with ageing. (C) 2010 Elsevier Inc. All rights reserved.
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