4.4 Review

Role of p62/SQSTM1 in liver physiology and pathogenesis

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Involvement of kinase PKC-zeta in the p62/p62P392L-driven activation of NF-κB in human osteoclasts

Estelle Chamoux et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)

Review Biochemistry & Molecular Biology

Ubiquitination and selective autophagy

S. Shaid et al.

CELL DEATH AND DIFFERENTIATION (2013)

Review Biochemistry & Molecular Biology

The multifaceted role of mTORC1 in the control of lipid metabolism

Stephane J. H. Ricoult et al.

EMBO REPORTS (2013)

Article Medicine, Research & Experimental

p62 Links beta-adrenergic input to mitochondrial function and thermogenesis

Timo D. Mueller et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Review Biochemistry & Molecular Biology

p62 at the Interface of Autophagy, Oxidative Stress Signaling, and Cancer

Ioannis P. Nezis et al.

ANTIOXIDANTS & REDOX SIGNALING (2012)

Review Biochemistry & Molecular Biology

mTOR Signaling in Growth Control and Disease

Mathieu Laplante et al.

Article Gastroenterology & Hepatology

Autophagy May Precede Cellular Senescence of Bile Ductular Cells in Ductular Reaction in Primary Biliary Cirrhosis

Motoko Sasaki et al.

DIGESTIVE DISEASES AND SCIENCES (2012)

Article Gastroenterology & Hepatology

Activation of autophagy protects against acetaminophen-induced hepatotoxicity

Hong-Min Ni et al.

HEPATOLOGY (2012)

Article Biochemistry & Molecular Biology

Sequestosome 1/p62, a Scaffolding Protein, Is a Newly Identified Partner of IRS-1 Protein

Thangiah Geetha et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

Parkin and Mitofusins Reciprocally Regulate Mitophagy and Mitochondrial Spheroid Formation

Wen-Xing Ding et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Multidisciplinary Sciences

Tissue Specific Induction of p62/Sqstm1 by Farnesoid X Receptor

Jessica A. Williams et al.

PLOS ONE (2012)

Review Pharmacology & Pharmacy

p62/SQSTM1/A170: Physiology and pathology

Masaaki Komatsu et al.

PHARMACOLOGICAL RESEARCH (2012)

Article Multidisciplinary Sciences

Keap1 degradation by autophagy for the maintenance of redox homeostasis

Keiko Taguchi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biochemistry & Molecular Biology

Chronic Activation of mTOR Complex 1 Is Sufficient to Cause Hepatocellular Carcinoma in Mice

Suchithra Menon et al.

SCIENCE SIGNALING (2012)

Review Biochemistry & Molecular Biology

p62: a versatile multitasker takes on cancer

Jorge Moscat et al.

TRENDS IN BIOCHEMICAL SCIENCES (2012)

Review Biochemistry & Molecular Biology

Amino acids and mTORC1: from lysosomes to disease

Alejo Efeyan et al.

TRENDS IN MOLECULAR MEDICINE (2012)

Review Cell Biology

Selective autophagy mediated by autophagic adapter proteins

Terje Johansen et al.

AUTOPHAGY (2011)

Review Biochemistry & Molecular Biology

Feedback on Fat: p62-mTORC1-Autophagy Connections

Jorge Moscat et al.

Review Cell Biology

NF-kappa B and STAT3 - key players in liver inflammation and cancer

Guobin He et al.

CELL RESEARCH (2011)

Article Cell Biology

Autophagy-deficient mice develop multiple liver tumors

Akito Takamura et al.

GENES & DEVELOPMENT (2011)

Article Biochemistry & Molecular Biology

Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy

Nickie C. Chan et al.

HUMAN MOLECULAR GENETICS (2011)

Article Biochemistry & Molecular Biology

Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane

Saori R. Yoshii et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Cell Biology

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

Yoshihiro Inami et al.

JOURNAL OF CELL BIOLOGY (2011)

Article Biochemistry & Molecular Biology

p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway

Angeles Duran et al.

MOLECULAR CELL (2011)

Article Biochemistry & Molecular Biology

Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins

Gen Matsumoto et al.

MOLECULAR CELL (2011)

Review Cell Biology

mTOR: from growth signal integration to cancer, diabetes and ageing

Roberto Zoncu et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)

Article Multidisciplinary Sciences

Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation

Ken-ichi Fujita et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Cardiac & Cardiovascular Systems

Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway

Narasimman Gurusamy et al.

CARDIOVASCULAR RESEARCH (2010)

Article Cell Biology

The role of the Atg1/ULK1 complex in autophagy regulation

Noboru Mizushima

CURRENT OPINION IN CELL BIOLOGY (2010)

Article Cell Biology

Mammalian autophagy: core molecular machinery and signaling regulation

Zhifen Yang et al.

CURRENT OPINION IN CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

Joo-Yong Lee et al.

EMBO JOURNAL (2010)

Article Biochemistry & Molecular Biology

A functional role for the p62-ERK1 axis in the control of energy homeostasis and adipogenesis

Sang Jun Lee et al.

EMBO REPORTS (2010)

Review Biochemistry & Molecular Biology

Physiological significance of selective degradation of p62 by autophagy

Masaaki Komatsu et al.

FEBS LETTERS (2010)

Article Gastroenterology & Hepatology

The Epidemiology of Obesity

Dang M. Nguyen et al.

GASTROENTEROLOGY CLINICS OF NORTH AMERICA (2010)

Article Biochemistry & Molecular Biology

PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation

Kazuhiro Nakamura et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Pathology

Recent advances in understanding the molecular basis of Paget disease of bone

A. Goode et al.

JOURNAL OF CLINICAL PATHOLOGY (2010)

Article Biochemistry & Molecular Biology

A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62

Alexandria Lau et al.

MOLECULAR AND CELLULAR BIOLOGY (2010)

Article Biochemistry & Molecular Biology

The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy

Maria Filimonenko et al.

MOLECULAR CELL (2010)

Article Multidisciplinary Sciences

Termination of autophagy and reformation of lysosomes regulated by mTOR

Li Yu et al.

NATURE (2010)

Article Cell Biology

Selective autophagy: ubiquitin-mediated recognition and beyond

Claudine Kraft et al.

NATURE CELL BIOLOGY (2010)

Article Cell Biology

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

Sven Geisler et al.

NATURE CELL BIOLOGY (2010)

Article Multidisciplinary Sciences

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

Cristofol Vives-Bauza et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra et al.

PLOS BIOLOGY (2010)

Review Biochemistry & Molecular Biology

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

Jorge Moscat et al.

Article Biochemistry & Molecular Biology

Autophagy Suppresses Tumorigenesis through Elimination of p62

Robin Mathew et al.

Review Biochemistry & Molecular Biology

Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex

J. Moscat et al.

CELL DEATH AND DIFFERENTIATION (2009)

Review Biochemistry & Molecular Biology

An Emerging Role of mTOR in Lipid Biosynthesis

Mathieu Laplante et al.

CURRENT BIOLOGY (2009)

Article Biochemistry & Molecular Biology

A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

Vladimir Kirkin et al.

MOLECULAR CELL (2009)

Article Cell Biology

Midbody ring disposal by autophagy is a post-abscission event of cytokinesis

Christian Pohl et al.

NATURE CELL BIOLOGY (2009)

Review Biochemistry & Molecular Biology

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

John D. Hayes et al.

TRENDS IN BIOCHEMICAL SCIENCES (2009)

Article Cell Biology

Selective turnover of p62/A170/SQSTM1 by autophagy

Yoshinobu Ichimura et al.

AUTOPHAGY (2008)

Review Biochemistry & Molecular Biology

Mallory-Denk-bodies: Lessons from keratin-containing hepatic inclusion bodies

R. Strnad et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2008)

Article Biochemistry & Molecular Biology

Structural basis for sorting mechanism of p62 in selective autophagy

Yoshinobu Ichimura et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Cell Biology

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Derek Narendra et al.

JOURNAL OF CELL BIOLOGY (2008)

Article Medicine, Research & Experimental

Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice

Wei Jin et al.

JOURNAL OF CLINICAL INVESTIGATION (2008)

Article Biochemistry & Molecular Biology

JNK1-mediated phosphorylation of BcI-2 regulates starvation-induced autophagy

Yongjie Wei et al.

MOLECULAR CELL (2008)

Review Pharmacology & Pharmacy

Dual roles of Nrf2 in cancer

Alexandria Lau et al.

PHARMACOLOGICAL RESEARCH (2008)

Article Multidisciplinary Sciences

Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

Peter Kijun Kim et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

Specific regulation of cytokine-dependent p38 MAP kinase activation by p62/SQSTM1

Kayoko Kawai et al.

JOURNAL OF BIOCHEMISTRY (2008)

Article Cell Biology

FoxO3 controls autophagy in skeletal muscle in vivo

Cristina Mammucari et al.

CELL METABOLISM (2007)

Article Biochemistry & Molecular Biology

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

Serhiy Pankiv et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Oncology

From Mallory to Mallory-Denk bodies: what, how and why?

Kurt Zatloukal et al.

EXPERIMENTAL CELL RESEARCH (2007)

Review Biochemistry & Molecular Biology

Signal integration and diversification through the p62 scaffold protein

Jorge Moscat et al.

TRENDS IN BIOCHEMICAL SCIENCES (2007)

Review Biochemistry & Molecular Biology

Sequestosome 1/p62 - More than just a scaffold

M. Lamar Seibenhener et al.

FEBS LETTERS (2007)

Review Biotechnology & Applied Microbiology

Potential therapeutic applications of autophagy

David C. Rubinsztein et al.

NATURE REVIEWS DRUG DISCOVERY (2007)

Article Multidisciplinary Sciences

Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates

Giovanni Solinas et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Toxicology

Intracellular signaling mechanisms of acetaminophen-induced liver cell death

H Jaeschke et al.

TOXICOLOGICAL SCIENCES (2006)

Article Pharmacology & Pharmacy

Mechanistic studies of the Nrf2-Keap1 signaling pathway

Donna D. Zhang

DRUG METABOLISM REVIEWS (2006)

Article Biochemistry & Molecular Biology

HDAC6 and microtubules are required for autophagic degradation of aggregated Huntingtin

A Iwata et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

The p62 scaffold regulates nerve growth factor-induced NF-κB activation by influencing TRAF6 polyubiquitination

MW Wooten et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

The role of MAPKs in adipocyte differentiation and obesity

F Bost et al.

BIOCHIMIE (2005)

Article Pathology

The proteasome inhibitor, PS-341, causes cytokeratin aggresome formation

F Bardag-Gorce et al.

EXPERIMENTAL AND MOLECULAR PATHOLOGY (2004)

Article Multidisciplinary Sciences

NF-κB functions as a tumour promoter in inflammation-associated cancer

E Pikarsky et al.

NATURE (2004)

Article Biochemistry & Molecular Biology

Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation

ML Seibenhener et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Gastroenterology & Hepatology

Obesity and hepatocellular carcinoma

SH Caldwell et al.

GASTROENTEROLOGY (2004)

Article Pathology

Bile acid-induced Mallory body formation in drug-primed mouse liver

P Fickert et al.

AMERICAN JOURNAL OF PATHOLOGY (2002)

Article Multidisciplinary Sciences

A central role for JNK in obesity and insulin resistance

J Hirosumi et al.

NATURE (2002)

Article Biochemistry & Molecular Biology

Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease

LJ Hocking et al.

HUMAN MOLECULAR GENETICS (2002)

Article Genetics & Heredity

Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone

N Laurin et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2002)

Article Pathology

p62 is a common component of cytoplasmic inclusions in protein aggregation diseases

K Zatloukal et al.

AMERICAN JOURNAL OF PATHOLOGY (2002)

Article Multidisciplinary Sciences

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

M Ramos-Gomez et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells

E Kuusisto et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)

Article Biochemistry & Molecular Biology

The atypical PKC-interacting protein p62 channels NF-κB activation by the IL-1-TRAF6 pathway

L Sanz et al.

EMBO JOURNAL (2000)