Journal
EXPERIMENTAL ANIMALS
Volume 58, Issue 4, Pages 333-341Publisher
INT PRESS EDITING CENTRE INC
DOI: 10.1538/expanim.58.333
Keywords
bioresource; ENU mutagenesis; NBRP-Rat; phenome project; RI strains
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Funding
- Japan Society for the Promotion of Science
- Ministry of Health, Labour and Welfare
- New Energy and Industrial Technology Development Organization (NEDO) of Japan
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In order to establish a system to facilitate the systematic collection, preservation, and provision of laboratory rats (Rattus norvegicus) and their derivates, the National BioResource Project-Rat (NBRP-Rat) was launched in July 2002. By the end of 2008, more than 500 rat strains had been collected and preserved as live animals, embryos, or sperm. These rat resources are supplied to biomedical scientists in Japan as well as in other countries. This review article introduces NBRP-Rat and highlights the phenome project, recombinant inbred strains, BAC clone libraries, and the ENU-mutant archive, named the Kyoto University Rat Mutant Archive (KURMA). The future direction of rat resources are also discussed.
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