Journal
EXERCISE AND SPORT SCIENCES REVIEWS
Volume 40, Issue 1, Pages 37-42Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/JES.0b013e3182348cdd
Keywords
feedforward control; feedback control; adrenergic; adenine nucleotides; purinergic receptors
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Funding
- National Institutes of Health [RO1 HL 82781]
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GORMAN, M. W. and E.O. FEIGL. Control of coronary blood flow during exercise. Exerc. Sport Sci. Rev., Vol. 40, No. 1, pp. 37-42, 2012. During exercise, coronary blood flow increases to match the augmented myocardial oxygen demand because of tachycardia. Coronary vasodilation during exercise is via a combination of feedforward and feedback control mechanisms. Feedforward control is mediated by sympathetic beta-adrenoceptor vasodilation. Feedback vasodilator control is via a novel hypothesis where adenine nucleotides released from red blood cells act on endothelial purinergic receptors.
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