Journal
EXERCISE AND SPORT SCIENCES REVIEWS
Volume 38, Issue 4, Pages 168-176Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/JES.0b013e3181f44f11
Keywords
colon cancer; wasting; inflammation; atrogin 1; exercise
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Funding
- National Institutes of Health, National Cancer Institute [1 R01 CA121249-01A2]
- NATIONAL CANCER INSTITUTE [R01CA121249] Funding Source: NIH RePORTER
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CARSON, J.A. and K. A. BALTGALVIS. Interleukin 6 as a key regulator of muscle mass during cachexia. Exerc. Sport Sci. Rev., Vol. 38, No. 4, pp. 168Y176, 2010. Interleukin 6 (IL-6) has received significant attention for its regulatory role in muscle wasting during cachexia. This review examines the role of circulating IL-6 for decreasing muscle mass during cancer and emphasizes some of the indirect actions of IL-6 that may cause muscle wasting.
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