Journal
EUROPEAN POLYMER JOURNAL
Volume 49, Issue 4, Pages 780-792Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.eurpolymj.2012.12.009
Keywords
Chitosan scaffolds; Biomaterials; Tissue engineering; Wound healing
Categories
Funding
- Belgian Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA)
- Science Policy Office of the Belgian Federal Government [IAP 7/05]
- Walloon Region
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Derived from chitin, chitosan is a unique biopolymer that exhibits outstanding properties, beside biocompatibility and biodegradability. Most of these peculiar properties arise from the presence of primary amines along the chitosan backbone. As a consequence, this polysaccharide is a relevant candidate in the field of biomaterials, especially for tissue engineering. The current article highlights the preparation and properties of innovative chitosan-based biomaterials, with respect to their future applications. The use of chitosan in 3D-scaffolds - as gels and sponges - and in 2D-scaffolds - as films and fibers - is discussed, with a special focus on wound healing application. (c) 2013 Elsevier Ltd. All rights reserved.
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