Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 137, Issue 15, Pages 4976-4979Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jacs.5b02700
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Funding
- European Union [312483]
- European Research Council under the European Union [311529]
- Alexander von Humboldt Foundation
- European Research Council (ERC) [311529] Funding Source: European Research Council (ERC)
- ICREA Funding Source: Custom
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We report on the synergy between catalytic propulsion and mesoporous silica nanoparticles (MSNPs) for the design of Janus nanomotors as active cargo delivery systems with sizes <100 nm (40, 65, and 90 nm). The Janus asymmetry of the nanomotors is given by electron beam (e-beam) deposition of a very thin platinum (2 nm) layer on MSNPs. The chemically powered Janus nanomotors present active diffusion at low H2O2 fuel concentration (i.e., <3 wt %). Their apparent diffusion coefficient is enhanced up to 100% compared to their Brownian motion. Due to their mesoporous architecture and small dimensions, they can load cargo molecules in large quantity and serve as active nanocarriers for directed cargo delivery on a chip.
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