Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 137, Issue 3, Pages 1341-1347Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja512212x
Keywords
-
Categories
Funding
- National Science Foundation for Young Scientists of China [21202156]
- National Natural Science Foundation of China [21372210, 21432009]
- Fundamental Research Funds for the Central Universities [WK2060190023]
- Natural Science Foundation of Anhui Province [1308085QB37]
- Nanyang Technological University
Ask authors/readers for more resources
Diverse and controllable pathways induced by palladium-catalyzed intramolecular Heck reaction of N-vinylacetamides for the synthesis of nitrogen-containing products in reasonable to high yields via tuning the phosphine ligands and bases are reported. Domino reactions including unique beta-N-Pd elimination, 1,4-Pd migration, or direct acyl C-H bond functionalization were found to be involved forming different products, respectively. Given the ability of using the same starting material to generate diverse products via completely different chemoselective processes, these current methodologies offer straightforward access to valuable nitrogen-containing products under mild reaction conditions as well as inspire the discovery of novel reactions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available