Journal
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
Volume 36, Issue 1, Pages 53-55Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.ejvs.2008.02.006
Keywords
symptomatic carotid stenosis; Imaging; MRI; positron emission tomography; stroke; USPIO
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Funding
- British Heart Foundation Funding Source: Medline
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Introduction: PET-FDG and USPIO-enhanced MRI are increasingly being used in depicting carotid atheroma inflammation - a risk factor for the high risk plaque. Their combined use has not been previously reported. Report: Two patients presenting with stroke and identified with 50% carotid stenosis on duplex ultrasonography, underwent PET FDG and USPIO-enhanced MR imaging. Results were concordant and complementary suggesting that both techniques reflect similar metabolic processes. Discussion: The selection of patients for carotid revascularisation has largely been based on the severity of luminal stenosis alone. The two imaging modalities, which identify inflammatory activity, may be potential surrogate risk markers in the selection of patients eligible for carotid surgery, if plaque inflammation can be correlated with risk of developing clinical symptoms. (C) 2008 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.
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