4.8 Article

Ipso-Borylation of Aryl Ethers via Ni-Catalyzed C-OMe Cleavage

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 137, Issue 21, Pages 6754-6757

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jacs.5b03955

Keywords

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Funding

  1. ICIQ
  2. European Research Council [ERC-277883]
  3. MINECO [CTQ2012-34054]
  4. MINECO (Severo Ochoa Excellence Accreditation) [SEV-2013-0319]
  5. Cellex Foundation
  6. MINECO
  7. ICREA Funding Source: Custom

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A Ni-catalyzed ipso-borylation of aryl ethers via C(sp(2))-OMe and C(sp(3))-OMe Cleavage is described. The transformation is characterized by its wide substrate scope tinder mild conditions and an exquisite divergence in Site selectivity that can be easily switched by selecting the appropriate, boron reagent.

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