Journal
EUROPEAN JOURNAL OF RADIOLOGY
Volume 78, Issue 1, Pages 21-29Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.ejrad.2010.07.028
Keywords
Diffusion magnetic resonance imaging; Pelvic neoplasms; Female
Funding
- Department of Health's NIHR Comprehensive Biomedical Research Centre
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Early applications of diffusion weighted magnetic resonance imaging (DWI) were limited to neuroimaging, concentrating either on stroke or brain tumours. With recent advances in MRI hardware and software DWI is now increasingly being investigated for cancer assessment throughout the body. Clinical applications of DWI relating to female pelvic cancers have largely concentrated on detection, localisation and staging of disease. More recently investigators have started to evaluate the ability of DWI for determining tumour histology and even predicting the outcome of chemoradiation treatment. This article reviews the physical concepts of MR diffusion weighting, illustrates the biophysical basis of diffusion contrast and reports the clinical applications of DWI for cervical, endometrial, ovarian, rectal and bladder tumours. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
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