4.5 Review

Detection and quantification of magnetically labeled cells by cellular MRI

Journal

EUROPEAN JOURNAL OF RADIOLOGY
Volume 70, Issue 2, Pages 258-264

Publisher

ELSEVIER IRELAND LTD
DOI: 10.1016/j.ejrad.2008.09.021

Keywords

MRI; Cell labeling; SPIO nanoparticles; Gadolinium; Perfluorocarbon

Funding

  1. Clinical Center at the National Institutes of Health
  2. CLINICAL CENTER [ZIACL090007] Funding Source: NIH RePORTER

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Labeling cells with superparamagnetic iron oxide (SPIO) nanoparticles, paramagnetic contrast agent (gadolinium) or perfluorocarbons allows for the possibility of tracking single or clusters of labeled cells within target tissues following either direct implantation or intravenous injection. This review summarizes the practical issues regarding detection and quantification of magnetically labeled cells with various MRI contrast agents with a focus on SPIO nanoparticles. Published by Elsevier Ireland Ltd.

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