Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 137, Issue 2, Pages 620-623Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja511911b
Keywords
-
Categories
Funding
- NSF [NSF CHE-1360634]
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [1360634] Funding Source: National Science Foundation
Ask authors/readers for more resources
The Ru-catalyzed alkene-alkyne coupling reaction has been demonstrated to be an enabling methodology for the synthesis of complex molecules. However, to date, it has been limited to monosubstituted olefins. Herein we report the first general utilization of disubstituted olefins in the Ru-catalyzed alkene-alkyne coupling reaction by employing carbamate directing groups. The products are stereodefined trisusbstituted enecarbamates. The elaboration of these structures toward the asymmetric synthesis of complex aminocyclopentitols and 1,2-amino alcohols is discussed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available