Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2014, Issue 14, Pages 2878-2882Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201400012
Keywords
Nitrogen heterocycles; Fused-ring systems; Amidation; Copper; C-H activation
Categories
Funding
- National Natural Science Foundation of China (NSFC) [21202167, 21072190, 21272233]
- Guangdong Natural Science Foundation [S2011020000806]
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An efficient synthesis of diverse indoline-2,3-diones from 2-aminoacetophenones through copper-catalyzed intramolecular C(sp(3))-H amidation is developed. The reaction proceeds in DMSO by using O-2 as the sole oxidant to provide the desired products in moderate to good yields.
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