Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2014, Issue 24, Pages 5281-5301Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201402426
Keywords
Multicomponent reactions; Nitrogen heterocycles; Fluorescence; Cross-coupling
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Funding
- Ministry of Education, Culture, Sports, Science and Technology (MEXT) (in part by the Global COE program Center for Practical Chemical Wisdom)
- Waseda University [2010A-874]
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We have successfully synthesized 3,4,5-substituted 1,4-dihydropyridines (1,4-DHPs) from amine hydrochloride salts, aldehydes, and acetals in good yields without the addition of a catalyst. The synthesized 1,4-DHPs exhibit various wavelengths of fluorescence, which could be tuned by changing the substituents at the 3- and 5-positions of the 1,4-DHPs.
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