4.5 Article

The First ZnII-Catalyzed Oxidative Amidation of Benzyl Alcohols with Amines under Solvent-Free Conditions

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2013, Issue 14, Pages 2783-2787

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201300367

Keywords

Zinc; Amidation; Benzyl alcohols; Amines; Oxidation

Funding

  1. state of Mecklenburg-Vorpommern
  2. Bundesministerium fur Bildung und Forschung (BMBF)

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The first zinc-catalyzed oxidative amidation of benzyl alcohols has been developed. Both aliphatic and aromatic amines can be tolerated and applied in this reaction. Various amides were prepared in good yields under solvent-free and mild conditions.

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