4.5 Article

Iridium-Catalyzed Direct Dehydroxylation of Alcohols

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2013, Issue 29, Pages 6496-6500

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201301293

Keywords

Synthetic methods; Dehydroxylation; Reduction; Iridium; Hydrazines; Alcohols

Funding

  1. Canada Research Chair Foundation
  2. Canada Foundation for Innovation (CFI)
  3. Fonds Quebecois de la Recherche sur la Nature et les Technologies (FQRNT) Center for Green Chemistry and Catalysis
  4. FQRNT Equipe
  5. Natural Sciences and Engineering Research Council of Canada (NSERC)
  6. McGill University

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Iridium-catalyzed direct dehydroxylation of alcohols with hydrazine was developed through a combination of the oxidation of alcohols and the Wolff-Kishner reduction. This protocol is simple to perform and highly efficient for a series of primary, benzylic and allylic alcohols.

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