Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2014, Issue 4, Pages 709-712Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201301512
Keywords
Synthetic methods; Amides; Fluorine; Iodine; Heterocycles
Categories
Funding
- National Natural Science Foundation of China (NSFC) [U1204205, 21202078, 21272110]
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A mild and efficient PhI(OAc)(2)-mediated trifluoromethylation reaction of N-arylacrylamides with TMSCF3 under metal-free conditions was developed. This method provides convenient access to a variety of useful CF3-containing oxindoles in moderate to good yields.
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