4.5 Article

NaOH-Catalyzed Imine Synthesis: Aerobic Oxidative Coupling of Alcohols and Amines

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2012, Issue 24, Pages 4457-4460

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201200716

Keywords

Imines; Oxidative coupling; Heterogeneous catalysis; Amines; Alcohols

Funding

  1. University Grants Commission (UGC)
  2. Council of Scientific and Industrial Research (CSIR), New Delhi, India
  3. CSIR/CSMCRI

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The convenient transition-metal-free synthesis of imines through oxidative coupling of alcohols and amines is reported. The reaction is catalyzed by NaOH (10 mol-%) and is performed with air as an oxidant in the absence of any co-solvent.

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