Recent Progress in Nickel-Catalyzed Biaryl Coupling

Nickel catalysis for biaryl coupling reactions has received significant attention as a less expensive and less toxic alternative to standard palladium catalysis. Here we describe recent developments in nickel-catalyzed biaryl coupling methodology, along with mechanistic studies and applications. In particular we focus on nickel-catalyzed coupling reactions in which unreactive bonds such as C-H, C-O, and C-C bonds are converted into biaryl moieties.