4.5 Article

Oxidative Ring Opening of 1,3-Diarylbenzo[c]heterocycles Using m-CPBA: Preparation of 1,2-Diaroylbenzenes

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2012, Issue 19, Pages 3647-3657

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201200311

Keywords

Synthetic methods; Heterocycles; Fused-ring systems; Oxidative cleavage; Selenium

Funding

  1. Department of Science and Technology (DST), New Delhi
  2. DST, New Delhi
  3. University Grants Commission (UGC), New Delhi
  4. Department of Science and Technology

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An unprecedented oxidative cleavage of benzo[c]heterocycles using m-CPBA is reported. The reaction of 1,3-diaryl benzo[c]heterocycles with m-CPBA (meta-chloroperoxybenzoic acid) at room temperature for 5 min led to the formation of 1,2-diaroylbenzenes in good to excellent yields.

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