Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2011, Issue 36, Pages 7308-7316Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201101053
Keywords
Synthesis design; Medicinal chemistry; Nitrogen heterocycles; Alk-ynes; Cycloisomerization
Categories
Funding
- National Natural Foundation of China (NSFC) [20872019]
- Fudan University
Ask authors/readers for more resources
A new tandem route leading to imidazo[1,2-a]pyridines has been explored through the direct amination of aryl propargylic alcohols with 2-aminopyridines and their subsequent intramolecular cycloisomerization. A ZnCl2/CuCl system has been developed to promote this transformation, which resulted in various imidazo[1,2-a]pyridines in moderate to good yields.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
