Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2011, Issue 36, Pages 7243-7253Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201100931
Keywords
Natural products; Nitrogen hetero-cycles; Alkaloids; Rearrangement; ss-Carbolines
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Funding
- Spanish Ministerio de Educacion y Ciencia (MEC) [CTQ2009-07738/BQU]
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beta-Carbolines are present in a wide variety of indole alkaloids that display important biological activities. Here we review the most recent aspects of the chemistry of beta-carbolines with a focus on functionalization of the beta-carboline system and transformations into other interesting compounds. Aromatizations, reductions and alkylations of the heterocyclic system are thus summarized first, followed by methodologies directed towards the formation of additional fused rings. Finally, rearrangements that transform beta-carbolines into other heterocyclic systems are covered.
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