Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2011, Issue 7, Pages 1207-1222Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201001520
Keywords
Natural products; Synthetic methods; Total synthesis; Aromatic substitution; Oxygen heterocycles; Cross-coupling; Diaryl ethers
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The structural variety of naturally occurring diaryl ethers is illustrated and the various synthetic methods employed for the construction of diaryl ether linkages in related total syntheses are reviewed. Examples of successful applications of each method (including reaction conditions, diaryl ether substitution pattern, and, when appropriate, the size of the ring formed) are given in tabular format.
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