4.5 Article

A New and Efficient Procedure for Bi(OTf)3-Promoted [3+2] Cycloaddition of N-Tosylaziridines to Yield Imidazolines

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2011, Issue 17, Pages 3122-3125

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201100270

Keywords

Heterocycles; Cycloaddition; N-Tosylaziridines; Imidazolines; Bismuth

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[3+2] Cycloaddition of a series of substituted N-tosylaziridines with various nitriles promoted by Bi(OTf)(3) is described for the synthesis of substituted imidazolines under mild reaction conditions. The procedure works well over a range of substrates to give the corresponding products in good to excellent yields (up to 99%).

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