Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2011, Issue 12, Pages 2301-2308Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201001581
Keywords
Nitrogen heterocycles; Green chemistry; Heterocycles; Water chemistry
Categories
Funding
- Department of Science and Technology (DST), New Delhi [SR/FTP/CS-58/2005]
- University Grants Commission (UGC), New Delhi
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A highly efficient green synthesis of aryl/alkyl/heteroaryl-substituted bis(6-amino-1,3-dimethyluracil-5-yl)methanes by the condensation of 6-amino-1,3-dimethyluracil with aldehydes (aromatic, aliphatic and heterocyclic) in water at room temperature is described. No dehydrating agent, heat, catalyst, surfactant or additive was used. The structures of the compounds were established by spectroscopic methods and single-crystal X-ray crystallography.
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