Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2011, Issue 10, Pages 1837-1840Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201001669
Keywords
C-C coupling; Cyclization; Nitrogen heterocycles; Medium-ring compounds; Palladium
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Funding
- Fund for Scientific Research (FWO), Flanders
- Katholieke Universiteit Leuven
- EMECW (Triple I)
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The regio- and stereoselective construction of the azocino[cd]indole core was achieved by applying a Pd-catalyzed intramolecular acetylene hydroarylation protocol. The applicability of a similar strategy for the synthesis of the azepino[b]indole framework is demonstrated.
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