Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2010, Issue 17, Pages 3205-3210Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201000220
Keywords
Amino acids; Carbocycles; Heterocycles; Organocatalysis; Domino reactions
Categories
Funding
- Department of Science and Technology (DST), New Delhi [DST/SR/SI/OC-65/2008]
- Council of Scientific and Industrial Research (CSIR), New Delhi
Ask authors/readers for more resources
A general process for the synthesis of substituted indenes and 1,2,3-triazoles was achieved for the first time through a multicatalysis cascade reaction of 2-ethynylbenzaldehydes, CH acids, organic hydrides, and azides in the presence of a catalytic amount of L-proline/CuI/DIPEA. In this communication, we discovered the utilization of a single copper catalyst for two different reactions and shown synthetic application to the high-yielding synthesis of glucocorticoid receptor modulators.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available