4.5 Article

An Efficient (2-Aminoarenethiolato)copper(I) Complex for the Copper-Catalysed Huisgen Reaction (CuAAC)

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2009, Issue 31, Pages 5423-5430

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200900779

Keywords

Azides; Alkynes; Click chemistry; Cycloaddition; Dendrimers; N ligands

Funding

  1. Italian Ministero dell'Universita e della Ricerca - Fondo Investimenti per la Ricerca di Base (FIRB) [RBNE033KMA]
  2. European Community [RIII-CT-2003-506350]

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A (2-aminoarenethiolato)copper(I) complex has been used as an efficient catalyst (1 mol-%) for the copper-catalysed Huisgen reaction (CuAAC) of azides and terminal alkynes in an organic solvent. The reaction was also extremely effective in CH2Cl2 allowing the complete decoration of dendrimeric scaffolds. (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

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