4.5 Article

Palladium-Catalyzed Three-Component Coupling Reactions: 1,1-Difunctionalization of Activated Alkenes

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2009, Issue 9, Pages 1313-1316

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200801245

Keywords

Palladium; C-C coupling; C-H activation; Iodine; Heck reaction

Funding

  1. University of Huddersfield

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A three-component coupling reaction was developed to access 3,3-oxyarylpropionate derivatives. Each of the three reaction components can be varied, allowing the modular synthesis of a range of important chiral building blocks. (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

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